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[当今的抗心律失常药物]

[Antiarrhythmic drugs in the present day].

作者信息

Allgaier R, Duncker D

机构信息

Hannover Herzrhythmus Centrum, Klinik für Kardiologie und Angiologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.

出版信息

Inn Med (Heidelb). 2024 Aug;65(8):762-769. doi: 10.1007/s00108-024-01745-9. Epub 2024 Jul 15.

Abstract

Cardiac arrhythmias cause a significant proportion of hospitalizations and physician contacts worldwide. By using antiarrhythmic drugs, cardiac arrhythmias can be effectively treated and the frequency of recurrences reduced. Atrial fibrillation and heart failure represent diseases in which antiarrhythmic drugs are more often used on a long-term basis. The aim of this article is to provide an overview of the most common antiarrhythmic drugs and their uses as well as to provide recommendations for adequate handling and use, especially in the outpatient setting. In addition to long-term use, some antiarrhythmic drugs are also administered for the acute management of supraventricular or ventricular tachycardia. Relevant contraindications, side effects and interactions must be considered, meaning that patients should be followed up when using these potent drugs. This article shows in detail what to consider when using antiarrhythmic drugs in order to ensure not only effective but also safe treatment.

摘要

心律失常导致全球相当一部分住院病例和医患接触。通过使用抗心律失常药物,可以有效治疗心律失常并降低复发频率。心房颤动和心力衰竭是更常长期使用抗心律失常药物的疾病。本文旨在概述最常用的抗心律失常药物及其用途,并提供适当处理和使用的建议,特别是在门诊环境中。除了长期使用外,一些抗心律失常药物还用于室上性或室性心动过速的急性处理。必须考虑相关的禁忌症、副作用和相互作用,这意味着在使用这些强效药物时应对患者进行随访。本文详细介绍了使用抗心律失常药物时应考虑的事项,以确保治疗不仅有效而且安全。

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