Key Laboratory of Biodiversity and Ecological Engineering of Jiangxi Province, Jinggangshan University, Ji'an, 343009, Jiangxi, China.
State Key Laboratory of Luminescent Materials and Devices, College of Materials Science and Engineering, South China University of Technology, Guangzhou, 510640, China.
Photochem Photobiol Sci. 2023 Jun;22(6):1245-1255. doi: 10.1007/s43630-023-00365-w. Epub 2023 Jan 24.
Liquids are perishable at ease during the long-term transportation and storage processes, non-invasive and in situ inspection method is urgent to be developed. In consideration of the important role of viscosity, one kind of sustainable natural product chlorogenic acid (CA) extracted from honeysuckle has been used as a versatile optical sensor for viscosity determination during the liquid spoilage process. The natural molecule was conducted by the O-diphenyl and carboxylic acid ester groups in coincidence, a typical twisted intramolecular charge transfer phenomenon was formed. This sensor features wide adaptability, high selectivity, good sensitivity, and excellent photo stability in various liquids. And CA displays a larger Stokes shift, high viscosity sensitive coefficient (0.62), and narrower energy band. The rotatable conjugate structure can be acted as the recognition site, and the bright fluorescent signal of CA is specifically activated when in the high viscous micro-environment. Inspired by this objective phenomenon, CA has been applied to detect the thickening efficiency of various food thickeners. More importantly, the viscosity fluctuations during the deterioration stage of liquids can be screened through non-invasive and in situ monitoring. We expected that more natural products can be developed as molecular tools for liquids safety investigation, and fluorescent analytical methods can be expanded toward interdisciplinary research.
液体在长途运输和储存过程中容易变质，因此急需开发一种非侵入式和原位检测方法。考虑到粘度的重要作用，一种从金银花中提取的可持续天然产物绿原酸 (CA) 已被用作液体变质过程中粘度测定的通用光学传感器。该天然分子通过邻苯二酚和羧酸酯基团的协同作用，形成了典型的扭曲分子内电荷转移现象。该传感器在各种液体中具有广泛的适应性、高选择性、良好的灵敏度和优异的光稳定性。CA 具有较大的斯托克斯位移、高粘度敏感系数（0.62）和较窄的能带。可旋转的共轭结构可作为识别位点，CA 的亮荧光信号在高粘性微环境中被特异性激活。受此客观现象的启发，CA 已被用于检测各种食品增稠剂的增稠效率。更重要的是，可以通过非侵入式和原位监测来筛选液体变质阶段的粘度波动。我们期望能够开发出更多的天然产物作为液体安全研究的分子工具，并将荧光分析方法扩展到跨学科研究。
