School of Biology and Biological Engineering, South China University of Technology, Guangzhou 510006, P. R. China.
Chem Commun (Camb). 2019 Feb 26;55(18):2688-2691. doi: 10.1039/c9cc00113a.
A lysosome-targeting dual-functional fluorescent probe was rationally designed and developed for imaging intracellular lysosomal viscosity and beta-amyloid. More importantly, the real-time tracking of the dynamic movement of lysosomes, as vesicle structures, has been achieved using Lyso-MC.
合理设计并开发了一种溶酶体靶向的双功能荧光探针，用于成像细胞内溶酶体黏度和β-淀粉样蛋白。更重要的是，使用 Lyso-MC 实现了对作为囊泡结构的溶酶体的动态运动的实时跟踪。
