Divyashree Krishna, Singh Harpreet, Suri Vikas, Bhalla Ashish
Department of Internal Medicine, 29751Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Trop Doct. 2023 Apr;53(2):321-324. doi: 10.1177/00494755231152654. Epub 2023 Jan 24.
Herpes simplex encephalitis is the most common cause of sporadic viral encephalitis worldwide but presents as a diagnostic challenge at many settings due to its non-specific symptoms, which can be easily mistaken for systemic infection or metabolic encephalopathy. It has diverse range of presentations from fever, altered sensorium, nausea, vomiting, meningismus to seizures, neurological deficits and coma in advanced stages. It is associated with significant morbidity and mortality if treatment is delayed or inadequate. We here discuss a case of Herpes simplex virus (HSV) encephalitis which rapidly progressed to result in irreversible neurological insult due to delayed diagnosis and treatment.
单纯疱疹病毒性脑炎是全球散发性病毒性脑炎最常见的病因，但由于其非特异性症状，在许多情况下都构成诊断挑战，这些症状很容易被误诊为全身感染或代谢性脑病。其临床表现多样，从发热、意识改变、恶心、呕吐、颈项强直到晚期的癫痫发作、神经功能缺损和昏迷。如果治疗延迟或不充分，会导致显著的发病率和死亡率。我们在此讨论一例单纯疱疹病毒（HSV）脑炎病例，由于诊断和治疗延迟，病情迅速进展，导致不可逆的神经损伤。
