Mahfouz Mohammad Eid M, Altowairqi Abdulmohsen Dubayyan M, Alghamdi Hussam Y, Alzahrani Mazen Saeed Z, Alqurashi Asim K, Alhuraity Talal H, Alqurashi Amr S
Surgical, Taif University, Taif, SAU.
College of Medicine, Taif University, Taif, SAU.
Cureus. 2022 Dec 22;14(12):e32827. doi: 10.7759/cureus.32827. eCollection 2022 Dec.
Post-cholecystectomy syndrome (PCS) refers to the continuation or recurrence of biliary colic and any other gastrointestinal symptoms present prior to cholecystectomy. Given that PCS is rare and underestimated in Saudi Arabia, this study aimed to determine the prevalence of PCS among Saudis.
This cross-sectional study included randomly gathered subjects who self-administered the validated European Organization for Research and Treatment of Cancer QLQ-C30 questionnaire from September 6 to October 7, 2022.
A total of 518 participants who underwent cholecystectomies were included; most were female (73.6%), 153 (29.5%) were 19 to 25 years old, and the vast majority were Saudi Arabian (91.1%). The average preoperative weight was 71 ± 20.7 kg (range 20 to 258), and the mean current weight was 69 ± 19.4 kg (range 30 to 257). About 137 (26.4%) had a chronic disease, most frequently hypertension (37.2%). In the past week, most participants experienced some trouble doing strenuous activities (42.9%), slight pain (37.6%), fatigue (32.2%), insomnia (37.5%), and weakness (38.2%). There were no significant associations between age, nationality, or residence with the QLQ-C30 score (P-value = 0.152, 0.262, 0.071, respectively). A significant association was observed between gender and QLQ-C30 score (P-value < 0.001), with females scoring higher than their male counterparts. Females also reported having a higher quality of life than males.
The prevalence of PCS was higher than reported elsewhere.
胆囊切除术后综合征（PCS）是指胆囊切除术前出现的胆绞痛及任何其他胃肠道症状持续存在或复发。鉴于沙特阿拉伯的PCS较为罕见且未得到充分认识，本研究旨在确定沙特人群中PCS的患病率。
本横断面研究纳入了2022年9月6日至10月7日期间随机选取并自行填写经过验证的欧洲癌症研究与治疗组织QLQ-C30问卷的受试者。
共纳入518例接受胆囊切除术的参与者；大多数为女性（73.6%），153例（29.5%）年龄在19至25岁之间，绝大多数为沙特阿拉伯人（91.1%）。术前平均体重为71±20.7千克（范围为20至258千克），目前平均体重为69±19.4千克（范围为30至257千克）。约137例（26.4%）患有慢性病，最常见的是高血压（37.2%）。在过去一周，大多数参与者在进行剧烈活动时遇到一些困难（42.9%）、有轻微疼痛（37.6%）、感到疲劳（32.2%）、失眠（37.5%）和虚弱（38.2%）。年龄、国籍或居住地与QLQ-C30评分之间无显著关联（P值分别为0.152、0.262、0.071）。性别与QLQ-C30评分之间存在显著关联（P值<0.001），女性得分高于男性。女性报告的生活质量也高于男性。
PCS的患病率高于其他地方的报道。
