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富白细胞血小板纤维蛋白在牙源性角化囊肿保守治疗中的应用:一例报告

Use of Leukocyte-PlateletRich Fibrin in Conservative Management of Odontogenic Keratocyst: A Case Report.

作者信息

Behnia Parsa, Malekigorji Mohsen, Tabrizi Reza, Dehghanpour Mehrdad, Ghaffarpasand Arash

机构信息

Department of Oral and Maxillofacial Surgery, School of dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

World J Plast Surg. 2022;11(3):98-102. doi: 10.52547/wjps.11.3.98.

DOI:10.52547/wjps.11.3.98
PMID:36694672
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9840757/
Abstract

A 29-year-old female patient was referred to the Department of Oral and Maxillofacial Surgery in Taleghani Hospital of Shahid Beheshti University of Medical Science, Tehran, Iran, in 2019, complaining of increased volume and pain in the posterior mandibular region. Cone-beam computed tomography and multislice computed tomography were performed, and an incisional biopsy was done. The histopathologic examination confirmed the diagnosis of Odontogenic Keratocyst (OKC). Surgical treatment was performed with marsupialization. After a year of follow-up, the resultant small-sized cyst was curetted, and Leukocyte-PlateletRich Fibrin (LPRF) was placed in the bony depression. The significant healing of the lesion was noted on regular follow-up visits with complete resolution at 15 months. This report showed that the application of LPRF might accelerate the healing of soft tissues and bone regeneration with no inhibitory effect on the natural healing process.

摘要

2019年,一名29岁女性患者被转诊至伊朗德黑兰沙希德·贝赫什提医科大学塔莱加尼医院口腔颌面外科,主诉下颌后部区域体积增大及疼痛。进行了锥形束计算机断层扫描和多层计算机断层扫描,并进行了切开活检。组织病理学检查确诊为牙源性角化囊肿(OKC)。采用袋形缝合术进行手术治疗。经过一年的随访,将形成的小型囊肿刮除,并在骨凹陷处放置富白细胞血小板纤维蛋白(LPRF)。在定期随访中注意到病变显著愈合,15个月时完全消退。本报告表明,LPRF的应用可能加速软组织愈合和骨再生,且对自然愈合过程无抑制作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba9d/9840757/acc2042ff409/wjps-11-98-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba9d/9840757/008ed60cf9dc/wjps-11-98-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba9d/9840757/b842d968bfd1/wjps-11-98-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba9d/9840757/acc2042ff409/wjps-11-98-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba9d/9840757/008ed60cf9dc/wjps-11-98-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba9d/9840757/b842d968bfd1/wjps-11-98-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba9d/9840757/acc2042ff409/wjps-11-98-g003.jpg

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本文引用的文献

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Autologous platelet concentrates in maxillofacial regenerative therapy.自体血小板浓缩物在颌面再生治疗中的应用。
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Management of an extensive odontogenic keratocyst: A rare case report with 10-year follow-up.广泛型牙源性角化囊肿的治疗:一例罕见病例报告及10年随访
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Odontogenic Cysts.牙源性囊肿
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