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在终端激活突触输入的体分流电缆模型中的瞬态响应。

Transient response in a somatic shunt cable model for synaptic input activated at the terminal.

作者信息

Poznanski R R

机构信息

Department of Mathematics, Monash University, Clayton, Victoria, Australia.

出版信息

J Theor Biol. 1987 Jul 7;127(1):31-50. doi: 10.1016/s0022-5193(87)80159-5.

Abstract

Rall's neuron model is extended by including a non-uniform time constant together with synaptic input modeled as a square step of conductance. An analytic solution (in series form) for the electrotonic potential is obtained. The major conclusion reached is that a lower somatic time constant attenuates the amplitude of the potential at the soma, brought about by the activation of a synapse located at the distal end of the dendritic cable in an initially polarized neuron.

摘要

通过纳入非均匀时间常数以及将突触输入建模为电导的方波,拉尔的神经元模型得到了扩展。得到了电紧张电位的解析解(级数形式)。得出的主要结论是,在初始极化的神经元中,较低的胞体时间常数会衰减由位于树突电缆远端的突触激活所引起的胞体电位幅度。

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