Poznanski R R, Gibson W G, Bennett M R
The Neurobiology Laboratory, Department of Physiology, University of Sydney, NSW, Australia.
Bull Math Biol. 1995 Nov;57(6):865-81. doi: 10.1007/BF03354909.
A model of a pair of electrotonically coupled CA3 hippocampal pyramidal neurons is presented. Each neuron is represented by a tapered equivalent cable attached to an isopotential soma. The synaptic potential in a neuron soma is determined as a consequence of electrical coupling to another soma that receives a synaptic input on its dendritic tree. Estimates of the coupling resistances, soma input resistances and soma-to-dendritic tree conductance ratio show that a substantial current may arise in a neuron as a consequence of synaptic activity in a neuron coupled to it. The small increase in decay time due to coupling in the model indicates that actual coupling is between more than just pairs of neurons.
本文提出了一对电耦合的CA3海马锥体神经元模型。每个神经元由连接到等电位胞体的锥形等效电缆表示。神经元胞体中的突触电位是由于与另一个在其树突树上接受突触输入的胞体进行电耦合而产生的。耦合电阻、胞体输入电阻和胞体与树突树电导比的估计表明，由于与其耦合的神经元中的突触活动，一个神经元中可能会产生大量电流。模型中由于耦合导致的衰减时间的小幅增加表明，实际的耦合不止发生在成对的神经元之间。
