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不同产地的巧茶中精神活性苯丙基和苯戊烯基卡他命的含量。

The content of psychoactive phenylpropyl and phenylpentenyl khatamines in Catha edulis Forsk. of different origin.

作者信息

Geisshüsler S, Brenneisen R

机构信息

Institute of Pharmacy, University of Berne, Switzerland.

出版信息

J Ethnopharmacol. 1987 May;19(3):269-77. doi: 10.1016/0378-8741(87)90004-3.

DOI:10.1016/0378-8741(87)90004-3
PMID:3669688
Abstract

Khat, the leaves of Catha edulis Forsk. (Celastraceae), is widely used as a stimulant in East Africa and the Arab Peninsula. Samples from the most important markets of Ethiopia, Kenya, North Yemen and Madagascar were analysed with high-performance liquid chromatography (HPLC) concerning their khatamine content (phenylpropyl and phenylpentenylamines). The variability of khatamines depending on origin, type and quality is discussed. In many samples a good correlation between the amount of cathinone, the main CNS-active compound, and quality estimation (price) of dealers and consumers was found.

摘要

巧茶,即Catha edulis Forsk.(卫矛科)的叶子,在东非和阿拉伯半岛被广泛用作兴奋剂。采用高效液相色谱法(HPLC)分析了来自埃塞俄比亚、肯尼亚、北也门和马达加斯加等最重要市场的样品中的巧茶胺含量(苯丙胺类和苯戊烯胺类)。讨论了巧茶胺因产地、类型和质量的变异性。在许多样品中,发现主要的中枢神经系统活性化合物去甲伪麻黄碱的含量与经销商和消费者的质量评估(价格)之间存在良好的相关性。

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J Ethnopharmacol. 1987 May;19(3):269-77. doi: 10.1016/0378-8741(87)90004-3.
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