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临床推理:一位 25 岁女性,眼部肿胀伴头痛。

Clinical Reasoning: A 25-Year-Old Woman With Eye Swelling and Headache.

机构信息

From the Department of Neurology (A.H., T.M., E.R.M.), and Department of Hematology (R.G.), University Hospital, GalwayDepartment of Neuroradiology (S.P.), Beaumont Hospital, Dublin, Ireland; and HRB Clinical Research Facility Galway (E.R.M.), National University of Ireland Galway.

出版信息

Neurology. 2023 May 2;100(18):879-883. doi: 10.1212/WNL.0000000000206836. Epub 2023 Jan 25.

Abstract

Cerebral venous sinus thrombosis (CVST) is uncommon. Risk factors include inherited and acquired factors. Rapid diagnosis and treatment is essential and can help prevent complications, which can include seizures and visual disturbance. A 25-year-old woman with a background history of CVST and intermittent warfarin use presented to the hospital in 2021 with a 3-month history of progressive eye swelling and headache. Her headache was located in the right frontal region and worsened with movement. Her workup was consistent with recurrent CVST and dural arteriovenous fistula. IR-guided embolization of the fistulas and stenting of her sinuses was performed. She was treated with dual antiplatelet therapy and therapeutic tinzaparin. Her symptoms improved markedly over several days, with improvement in headache and visual acuity. This case illustrates the potential for severe complications including visual disturbance in untreated CVST, as well as the importance of a thorough history and examination in aiding the recognition of the condition.

摘要

脑静脉窦血栓形成(CVST)并不常见。危险因素包括遗传性和获得性因素。快速诊断和治疗至关重要,可以帮助预防并发症,包括癫痫发作和视力障碍。一位 25 岁的女性,有 CVST 病史和间歇性华法林使用史,于 2021 年因 3 个月的进行性眼球肿胀和头痛就诊。她的头痛位于右额区,活动时加重。她的检查结果与复发性 CVST 和硬脑膜动静脉瘘相符。对瘘管进行了 IR 引导下栓塞和窦道支架置入。她接受了双联抗血小板治疗和治疗性达肝素钠治疗。经过几天的治疗,她的症状明显改善,头痛和视力均有所改善。本例说明了未经治疗的 CVST 可能导致严重并发症,包括视力障碍,以及全面的病史和检查对于识别该疾病的重要性。

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Clinical Reasoning: A 25-Year-Old Woman With Eye Swelling and Headache.临床推理:一位 25 岁女性,眼部肿胀伴头痛。
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本文引用的文献

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Intracranial dural arteriovenous fistulas: A Review.颅内硬脑膜动静脉瘘:综述
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