Röher H D, Goretzki P E, Wahl R A
Zentrum Operative Medizin I, Klinik für Allgemeine und Unfallchirurgie der Medizinischen Einrichtungen, Universität Düsseldorf.
Langenbecks Arch Chir. 1987;371(2):103-13. doi: 10.1007/BF01251902.
84 (19.5%) of 431 patients with differentiated thyroid cancer developed distant metastases in bone and parenchymal organs. 78% of primary bone metastases and only 21% of primary lung metastases were treated operatively. High survival rates of 33-60% at 5 years supported the necessity of surgical interventions primarily in bone metastases to prevent early morbidity due to pathological fractures. Even in case of questionable increase in survival rate surgery of metastases from differentiated thyroid carcinomas doubtlessly improves the quality of life in these patients.
431例分化型甲状腺癌患者中有84例（19.5%）发生了骨和实质器官的远处转移。原发性骨转移的78%和原发性肺转移的仅21%接受了手术治疗。5年生存率高达33% - 60%，这支持了主要对骨转移进行手术干预以预防病理性骨折导致的早期发病的必要性。即使在分化型甲状腺癌转移灶的生存率提高情况存疑的情况下，对这些转移灶进行手术无疑能改善患者的生活质量。
