Tsin A T, Flores J M, Rodriguez K A
Division of Life Sciences, University of Texas at San Antonio 78285.
Life Sci. 1987 Nov 2;41(18):2085-90. doi: 10.1016/0024-3205(87)90525-x.
The visual cells, visual pigments and major retinoids of the Mongolian jird (Meriones unguiculatus) were examined. Light and electron microscope analyses show that these jirds had mainly rod photoreceptors. Octylglucoside extracts prepared from their retinas contained only rhodopsin with a maximum absorption at 497 nm and a concentration of 0.51 nmol per retina. Employing a standard method of high performance liquid chromatography (HPLC), the pigment epithelium from each eye was found to possess 0.52 nmol of retinyl palmitate (the most abundant form of retinyl ester) along with a small amount of retinol (0.02 nmol). Most of the retinoids in the body of these animals are stored in the liver, in the form of retinyl palmitate (1228.80 nmol per gram liver). As the Mongolian jird is small, inexpensive and readily available, this animal is a mammalian species suitable for the research of the biochemistry of retinoids and vision.
对长爪沙鼠（Meriones unguiculatus）的视觉细胞、视觉色素和主要类视黄醇进行了检测。光学显微镜和电子显微镜分析表明，这些长爪沙鼠主要具有视杆光感受器。从其视网膜制备的辛基葡糖苷提取物仅含有视紫红质，其最大吸收波长为497nm，每个视网膜的浓度为0.51nmol。采用高效液相色谱（HPLC）标准方法，发现每只眼睛的色素上皮含有0.52nmol的棕榈酸视黄酯（视黄酯最丰富的形式）以及少量视黄醇（0.02nmol）。这些动物体内的大部分类视黄醇以棕榈酸视黄酯的形式储存在肝脏中（每克肝脏1228.80nmol）。由于长爪沙鼠体型小、价格低廉且易于获取，这种动物是适合进行类视黄醇和视觉生物化学研究的哺乳动物物种。
