Huang Pei-Pei, Poon Samantha Yun-Kai, Chang Shao-Hsuan, Kuo Chien-Wen, Chien Ming-Wen, Chen Chien-Chih, Chiang Shao-Chin
Division of Outpatient Pharmacy, Department of Pharmacy, Cheng Hsin General Hospital, Taipei, Taiwan.
Department of Pharmacy, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University (Yang Ming Campus), Taipei, Taiwan.
Int J Gen Med. 2023 Jan 19;16:211-220. doi: 10.2147/IJGM.S389683. eCollection 2023.
Medication reconciliation (MedRec) is a process to ensure complete and accurate communication of patient medication information throughout care transitions to prevent medication errors. Hospitals in Taiwan have stride to implement a universal protocol for MedRec. To establish a feasible protocol indigenously, the World Health Organization (WHO) protocol was incorporated with the Taiwan National Health Insurance (NHI) PharmaCloud patient medication profile. The efficiency and error detection capability of this modified protocol was evaluated in two hospitals.
A prospective, non-randomized, unblinded, multicenter cohort study was conducted. Subjects were recruited among patients admitted for colorectal or orthopedic surgery with at least 4 or more chronic drugs. To obtain the best possible medication history (BPMH), the control group was conducted according to the WHO protocol, and the experimental group used the modified WHO protocol with the medication data from the PharmaCloud system. The time spent on the two protocols was recorded. Admission and discharge orders were reconciled against the BPMH to identify any discrepancies. Discrepancies were evaluated by appropriateness, prescribing intentions, and types of inappropriateness. The levels of potential harm were classified for inappropriate discrepancies.
The mean time to obtain BPMH in the control group was 34.3±10.8 minutes and in the experimental group 27.5±11.5 minutes ( = 0.01). The experimental group had more subjects with discrepancies (87.9%) than the control (58.3%) ( < 0.001). The discrepancies in both admission and discharge orders for the experimental group (84.5 and 67.2%) were higher than those of the control (47.9 and 37.5%). Many inappropriate discrepancies were classified as the potential harm of level 2 (77.8%).
Through the establishment of BPMH with the medication data from the Taiwan NHI PharmaCloud, MedRec could be achieved with greater efficiency and error detection capability in both the admission and discharge order validation processes.
用药核对(MedRec)是一个确保患者用药信息在整个护理转接过程中完整准确传递以预防用药错误的过程。台湾的医院一直在努力实施通用的MedRec方案。为了本土建立可行的方案,世界卫生组织(WHO)的方案与台湾全民健康保险(NHI)的医药云患者用药档案相结合。在两家医院评估了这种改良方案的效率和错误检测能力。
进行了一项前瞻性、非随机、非盲法、多中心队列研究。在因结直肠或骨科手术入院且至少服用4种或更多种慢性药物的患者中招募研究对象。为了获取尽可能完善的用药史(BPMH),对照组按照WHO方案进行,实验组使用结合了医药云系统用药数据的改良WHO方案。记录完成两种方案所花费的时间。将入院和出院医嘱与BPMH进行核对以识别任何差异。通过适宜性、处方意图和不适宜类型对差异进行评估。对不适宜差异的潜在危害程度进行分类。
对照组获取BPMH的平均时间为34.3±10.8分钟,实验组为27.5±11.5分钟(P = 0.01)。实验组有差异的研究对象(87.9%)比对照组(58.3%)更多(P < 0.001)。实验组入院和出院医嘱的差异(分别为84.5%和67.2%)高于对照组(分别为47.9%和37.5%)。许多不适宜差异被归类为2级潜在危害(77.8%)。
通过利用台湾NHI医药云的用药数据建立BPMH,在入院和出院医嘱验证过程中,MedRec能够以更高的效率和错误检测能力实现。