Pang Kun, Pan Deng, Xu Hao, Ma Yuyang, Wang Jingkai, Xu Peng, Wang Hailuo, Zang Guanghui
Department of Urology, Xuzhou Central Hospital, Xuzhou Clinical College of Xuzhou Medical University, The Affiliated Xuzhou Hospital of Medical College of Southeast University, The Affiliated Xuzhou Center Hospital of Nanjing University of Chinese Medicine, Xuzhou, Jiangsu, China.
Graduate School, Bengbu Medical College, Bengbu, Anhui, China.
Front Physiol. 2023 Jan 9;13:1096741. doi: 10.3389/fphys.2022.1096741. eCollection 2022.
Erectile dysfunction (ED) is the most common male sexual dysfunction by far and the prevalence is increasing year after year. As technology advances, a wide range of physical diagnosis tools and therapeutic approaches have been developed for ED. At present, typical diagnostic devices include erection basic parameter measuring instrument, erection hardness quantitative analysis system, hemodynamic testing equipment, nocturnal erection measuring instrument, nerve conduction testing equipment, At present, the most commonly used treatment for ED is pharmacological therapy represented by phosphodiesterase five inhibitors (PDE5i). As a first-line drug in clinical, PDE5i has outstanding clinical effects, but there are still some problems that deserve the attention of researchers, such as cost issues and some side effects, like visual disturbances, indigestion, myalgia, and back pain, as well as some non-response rates. Some patients have to consider alternative treatments. Moreover, the efficacy in some angiogenic EDs (diabetes and cardiovascular disease) has not met expectations, so there is still a need to continuously develop new methods that can improve hemodynamics. While drug have now been shown to be effective in treating ED, they only control symptoms and do not restore function in most cases. The increasing prevalence of ED also makes us more motivated to find safer, more effective, and simpler treatments. The exploration of relevant mechanisms can also serve as a springboard for the development of more clinically meaningful physiotherapy approaches. Therefore, people are currently devoted to studying the effects of physical therapy and physical therapy combined with drug therapy on ED. We reviewed the diagnosis of ED and related physical therapy methods, and explored the pathogenesis of ED. In our opinion, these treatment methods could help many ED patients recover fully or partially from ED within the next few decades.
勃起功能障碍(ED)是目前最常见的男性性功能障碍,且患病率逐年上升。随着技术的进步,针对勃起功能障碍已开发出多种物理诊断工具和治疗方法。目前,典型的诊断设备包括勃起基本参数测量仪、勃起硬度定量分析系统、血流动力学检测设备、夜间勃起测量仪、神经传导检测设备。目前,治疗勃起功能障碍最常用的方法是以磷酸二酯酶5抑制剂(PDE5i)为代表的药物治疗。作为临床一线药物,PDE5i具有出色的临床效果,但仍存在一些值得研究人员关注的问题,如成本问题以及一些副作用,如视觉障碍、消化不良、肌痛和背痛,还有一些无反应率。一些患者不得不考虑其他治疗方法。此外,在一些血管生成性勃起功能障碍(糖尿病和心血管疾病)中的疗效未达预期,因此仍需要不断开发能够改善血流动力学的新方法。虽然药物现已被证明对治疗勃起功能障碍有效,但在大多数情况下,它们仅能控制症状,无法恢复功能。勃起功能障碍患病率的上升也促使我们更积极地寻找更安全、更有效、更简便的治疗方法。对相关机制的探索也可为开发更具临床意义的物理治疗方法提供跳板。因此,目前人们致力于研究物理治疗以及物理治疗与药物治疗相结合对勃起功能障碍的影响。我们回顾了勃起功能障碍的诊断及相关物理治疗方法,并探讨了勃起功能障碍的发病机制。我们认为,在未来几十年内,这些治疗方法可帮助许多勃起功能障碍患者完全或部分康复。