Hospital Clínico Universitario Virgen de la Arrixaca, Microbiology Service, El Palmar, Murcia, Spain.
Universidad de Murcia, Microbiology and Genetics Department, Murcia, Spain.
Rev Soc Bras Med Trop. 2023 Jan 23;56. doi: 10.1590/0037-8682-0384-2022. eCollection 2023.
Chagas disease (CD) treatment is commonly associated with a high incidence of adverse effects. It is crucial to study and update these adverse effects to improve the existing knowledge of which drugs to use and to clarify the information presented to patients.
We analyzed the adverse effects of benznidazole in two cohorts of patients: a large retrospective study and a small prospective study.
This large retrospective study described the most and least common adverse effects in our area and characterized our Chagas disease population. This prospective study, along with a close follow-up of the treatment, detected more adverse effects and enhanced the patients' perception of the disease and treatment.
This information is important for preventing non-medical-related withdrawals and for removing baseless fears. Better knowledge of patients could help us provide better care.
恰加斯病（CD）的治疗通常伴随着较高的不良反应发生率。研究和更新这些不良反应至关重要，这有助于提高现有药物使用知识，并澄清向患者提供的信息。
我们分析了苯达唑在两个患者队列中的不良反应：一项大型回顾性研究和一项小型前瞻性研究。
这项大型回顾性研究描述了我们地区最常见和最不常见的不良反应，并对我们的恰加斯病人群进行了特征描述。这项前瞻性研究，加上对治疗的密切随访，检测到了更多的不良反应，并增强了患者对疾病和治疗的认知。
这些信息对于防止非医疗原因的停药和消除毫无根据的恐惧非常重要。更好地了解患者可以帮助我们提供更好的护理。
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