Kargarghomsheh Pegah, Naghashan Mahsa, Farhadiyan Soraya, Arabameri Majid, Tooryan Fahimeh, Shariatifar Nabi
Department of Food Science, University of Massachusetts, Amherst, MA, 01003, USA.
Department of Food Science and Technology, Ferdowsi University of Mashhad, Mashhad, Iran.
Environ Sci Pollut Res Int. 2023 Mar;30(15):44833-44844. doi: 10.1007/s11356-023-25313-0. Epub 2023 Jan 26.
In the present study, magnetic solid phase extraction (MSPE) method and gas chromatography-mass spectrometry (GC/MS) technique were used to measure 6 PAE in fruit juice samples. The mean of total phthalic acid esters (ƩPAEs) in all samples was 3.55 ± 0.66 µg/L. The mean concentration of DEHP (bis(2-ethylhexyl) phthalate) in samples was 0.82 ± 0.31 µg/L, which was lower than the mentioned United States Environmental Protection Agency (USEPA) standard level in drinking water (6 μg/L for DEHP). The pineapple juice samples (4.44 ± 0.57 µg/L) and mango juice samples (2.77 ± 0. 1 µg/L) had maximum and minimum mean levels of ƩPAEs, respectively. Also, results showed that brand B (3.76 ± 0.87 µg/L) and samples in the time of expiration date (3.64 ± 0.72 µg/L) had the highest PAE levels. The rank order Chronic Daily Intake (95%) values for adults were DEHP ([Formula: see text]) > butylbenzyl phthalates (BBP) ([Formula: see text]) > diethyl phthalate (DEP) ([Formula: see text]) and for children were DEHP ([Formula: see text]) > BBP (9.07E-04) > DEP ([Formula: see text]), which were below the tolerable daily intake (TDI) value. The noncancer risk of PAEs based on the target hazard quotient (THQ) was acceptable (< 1). The results exhibited that the Incremental Lifetime Cancer Risk (ILCR) was below the permissible limit (< [Formula: see text]). Therefore, the risk of carcinogenicity and noncarcinogenicity of PAEs in juices does not have adverse effects on human health.
在本研究中，采用磁性固相萃取（MSPE）法和气相色谱 - 质谱联用（GC/MS）技术测定果汁样品中的6种邻苯二甲酸酯类物质。所有样品中总邻苯二甲酸酯（ƩPAEs）的平均值为3.55±0.66μg/L。样品中邻苯二甲酸二（2-乙基己基）酯（DEHP）的平均浓度为0.82±0.31μg/L，低于美国环境保护局（USEPA）规定的饮用水标准水平（DEHP为6μg/L）。菠萝汁样品（4.44±0.57μg/L）和芒果汁样品（2.77±0.1μg/L）中ƩPAEs的平均含量分别最高和最低。此外，结果表明品牌B（3.76±0.87μg/L）和过期日期时的样品（3.64±0.72μg/L）中PAE含量最高。成人慢性每日摄入量（95%）值的排序为DEHP（[公式：见原文]）>邻苯二甲酸丁苄酯（BBP）（[公式：见原文]）>邻苯二甲酸二乙酯（DEP）（[公式：见原文]），儿童的排序为DEHP（[公式：见原文]）>BBP（9.07E - 04）>DEP（[公式：见原文]），均低于每日耐受摄入量（TDI）值。基于目标危害商（THQ）的PAEs非致癌风险是可接受的（<1）。结果显示增量终生癌症风险（ILCR）低于允许限值（<[公式：见原文]）。因此，果汁中PAEs的致癌和非致癌风险对人体健康没有不良影响。
