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酒精戒断谵妄导致腰椎爆裂性骨折的疑难病例报告

A challenging case of lumbar vertebral burst fracture with alcohol withdrawal delirium: A case report.

机构信息

Department of Orthopaedic Surgery, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, Japan.

出版信息

Medicine (Baltimore). 2023 Jan 20;102(3):e32712. doi: 10.1097/MD.0000000000032712.

Abstract

BACKGROUND

Delirium tremens is a symptom of alcohol withdrawal syndrome that occurs 48 to 96 hours after the last drink in 5% of withdrawing patients.

METHODS

This report describes the clinical progression of a case of lumbar vertebral burst fracture with alcohol withdrawal delirium that was difficult to manage.

RESULTS

A 47-year-old man was rushed to our hospital complaining of lumbar back pain and numbness in both lower extremities resulting from a 6-m fall during civil engineering work. Computed tomography (CT) revealed a L1 burst fracture with a highly protruding bone fragment in the spinal canal. Magnetic resonance imaging disclosed significant compression of the conus and intramedullary signal changes. We immediately performed posterior spinal fusion and vertebroplasty using instrumentation. On the 4th postoperative day, he became severely agitated, as diagnosed as having delirium tremens related to alcohol withdrawal syndrome, and soon began appropriate medication with diazepam. Although his symptoms persisted until 6 days postoperatively, follow-up CT detected no evidence of screw loosening or breakage.

CONCLUSION

We encountered a patient with severe delirium tremens developing several days after thoraco-lumbar fusion surgery. Prompt internal fixation successfully treated the spinal injury and prevented neurological damage. It may also be necessary to consider treatment strategies for patients with a background of heavy alcohol consumption in consideration of delirium tremens and other symptoms of alcohol withdrawal.

摘要

背景

震颤谵妄是酒精戒断综合征的一种症状,在 5%的戒断患者中,会在最后一次饮酒后 48 至 96 小时出现。

方法

本报告描述了一例腰椎爆裂性骨折合并酒精戒断性谵妄的病例,该病例的临床进展较为复杂,难以处理。

结果

一名 47 岁男性在土木工程工作中从 6 米高处坠落,导致腰痛和双下肢麻木,被紧急送往我院。计算机断层扫描(CT)显示 L1 爆裂性骨折,椎管内有高度突出的骨块。磁共振成像(MRI)显示圆锥明显受压和髓内信号改变。我们立即使用器械进行后路脊柱融合和椎体成形术。术后第 4 天,他出现严重的激动状态,被诊断为与酒精戒断综合征相关的震颤谵妄,并立即开始使用地西泮进行适当的药物治疗。尽管他的症状持续到术后 6 天,但随访 CT 未发现螺钉松动或断裂的证据。

结论

我们遇到了一名在胸腰椎融合手术后几天出现严重震颤谵妄的患者。及时的内固定成功治疗了脊柱损伤并防止了神经损伤。对于有大量饮酒背景的患者,可能还需要考虑治疗策略,以考虑震颤谵妄和其他酒精戒断症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c81/9857445/3746906085f4/medi-102-e32712-g001.jpg

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