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基线睡眠特征与失眠认知行为疗法后睡眠持续时间的增加有关。

Baseline sleep characteristics are associated with gains in sleep duration after cognitive behavioral therapy for insomnia.

机构信息

Adelaide Institute for Sleep Health, A Flinders Centre of Research Excellence, College of Medicine and Public Health, Flinders University, Adelaide, Australia.

School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.

出版信息

Sleep Med. 2023 Feb;102:199-204. doi: 10.1016/j.sleep.2023.01.009. Epub 2023 Jan 14.

Abstract

OBJECTIVE/BACKGROUND: Cognitive behavioural therapy for insomnia (CBT-I) substantially reduces total wake time (TWT) by the end of treatment. In contrast, total sleep time (TST) does not increase above baseline levels for most patients following 4-8 sessions of treatment. In the 6-12 months following CBT-I, without any further intervention, up to 64% of participants substantially increase their TST (by ≥ 30 min). The current study investigated which baseline characteristics are associated with increases in TST after CBT-I.

PATIENTS/METHODS: Data were analysed from a randomised controlled trial assessing acute and maintenance CBT-I (N = 80). Linear mixed models were conducted to assess the effect of baseline characteristics on changes in TST up to 24 months after CBT-I. Baseline characteristics included age, sex, marital status, sleep continuity (derived from sleep diaries and polysomnography studies), and mental health and quality of life questionnaires.

RESULTS

At baseline, self-reported sleep latency, wake after sleep onset, early morning awakenings, TWT, TST, and sleep efficiency were associated with the greatest changes in TST (p < .03 for interactions), such that patients who reported more wake/less sleep at baseline also reported the largest increases in TST. No other baseline variables were associated with changes in TST after CBT-I, including age, sex, and polysomnography-derived sleep continuity (p > .07 for interactions).

CONCLUSIONS

Patients with more severe self-reported sleep difficulties and lower sleep duration at baseline showed greater improvements in TST after CBT-I. Whether more patients could increase their TST, within the context of acute treatment or following treatment, warrants investigation.

摘要

目的/背景:认知行为疗法治疗失眠症(CBT-I)在治疗结束时可显著减少总清醒时间(TWT)。相比之下,对于大多数患者,在接受 4-8 次治疗后,总睡眠时间(TST)不会高于基线水平。在接受 CBT-I 后的 6-12 个月内,如果没有进一步的干预,多达 64%的参与者的 TST 会显著增加(增加≥30 分钟)。本研究调查了哪些基线特征与 CBT-I 后 TST 的增加有关。

患者/方法:对一项评估急性和维持性 CBT-I 的随机对照试验的数据进行了分析(N=80)。线性混合模型用于评估基线特征对 CBT-I 后 24 个月内 TST 变化的影响。基线特征包括年龄、性别、婚姻状况、睡眠连续性(来自睡眠日记和多导睡眠图研究)以及心理健康和生活质量问卷。

结果

在基线时,自我报告的入睡潜伏期、睡眠后觉醒时间、清晨觉醒、TWT、TST 和睡眠效率与 TST 的最大变化相关(交互作用的 p<0.03),即基线时报告更多觉醒/更少睡眠的患者报告 TST 增加幅度最大。其他基线变量与 CBT-I 后 TST 的变化无关,包括年龄、性别和多导睡眠图衍生的睡眠连续性(交互作用的 p>0.07)。

结论

基线时自我报告的睡眠困难更严重且睡眠时间更短的患者在接受 CBT-I 后 TST 改善更大。是否可以有更多的患者在急性治疗或治疗后增加他们的 TST,这值得进一步研究。

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