Korzhov V I
Ukr Biokhim Zh (1978). 1979 Mar-Apr;51(2):147-50.
The data of studies on proton metabolism in mitochondria of the guinea pig lungs and liver with application of benemycin and sodium succinate show that benemycin does not affect the metabolism of protons in the lungs and liver mitochondria. Sodium succinate activates the release of protons from the lungs and liver mitochondria in state 4 according to Chance. When using sodium succinate for reducing the effect of benemycin on theorganism it is found that sodium succinate inhibits the utilization of protons of the lungs and liver mitochondria in state 3 according to Chance and activates this release in state 4, thus favouring an increase in their concentration in the extra-mitochondrial space. Sodium succinate increases survival rate of animals which were administered benemycin to.
关于在豚鼠肺和肝线粒体中应用贝尼霉素和琥珀酸钠对质子代谢进行研究的数据表明，贝尼霉素不影响肺和肝线粒体中的质子代谢。根据钱斯的理论，琥珀酸钠在状态4时能激活肺和肝线粒体中质子的释放。当使用琥珀酸钠来降低贝尼霉素对机体的影响时，发现琥珀酸钠在状态3时抑制肺和肝线粒体中质子的利用，并在状态4时激活这种释放，从而有利于线粒体外空间中质子浓度的增加。琥珀酸钠可提高给予贝尼霉素的动物的存活率。
