Zheng Wenwen, Li Junjun, Wang Yu, Ye Zhuyifan, Zhong Hao, Kot Hung Wan, Ouyang Defang, Chan Ging
Department of Clinical Laboratory, The Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences (ICMS), University of Macau, Macau, China.
Curr Comput Aided Drug Des. 2023;19(6):405-415. doi: 10.2174/1573409919666230126095901.
This article aims to quantitatively analyze the growth trend of listed pharmaceutical companies in the US and China by a machine learning algorithm.
In the last two decades, the global pharmaceutical industry has faced the dilemma of low research & development (R&D) success rate. The US is the world's largest pharmaceutical market, while China is the largest emerging market.
To collect data from the database and apply machine learning to build the model.
LightGBM algorithm was used to build the model and identify the factor important to the performance of pharmaceutical companies.
The prediction accuracy for US companies was 80.3%, while it was 64.9% for Chinese companies. The feature importance shows that the net profit growth rate and debt liability ratio are significant in financial indicators. The results indicated that the US may continue to dominate the global pharmaceutical industry, while several Chinese pharmaceutical companies rose sharply after 2015 with the narrowing gap between the Chinese and US pharmaceutical industries.
In summary, our research quantitatively analyzed the growth trend of listed pharmaceutical companies in the US and China by a machine learning algorithm, which provide a novel perspective for the global pharmaceutical industry. According to the R&D capability and profitability, 141 US-listed and 129 China-listed pharmaceutical companies were divided into four levels to evaluate the growth trend of pharmaceutical firms.
本文旨在通过机器学习算法对美国和中国上市制药公司的增长趋势进行定量分析。
在过去二十年中,全球制药行业面临研发成功率低的困境。美国是世界上最大的制药市场,而中国是最大的新兴市场。
从数据库收集数据并应用机器学习来构建模型。
使用LightGBM算法构建模型并确定对制药公司业绩重要的因素。
美国公司的预测准确率为80.3%,而中国公司为64.9%。特征重要性表明,净利润增长率和资产负债率在财务指标中具有重要意义。结果表明,美国可能继续主导全球制药行业,而几家中国制药公司在2015年后大幅崛起,中美制药行业之间的差距正在缩小。
综上所述,我们的研究通过机器学习算法对美国和中国上市制药公司的增长趋势进行了定量分析,为全球制药行业提供了一个新的视角。根据研发能力和盈利能力,将141家美国上市和129家中国上市制药公司分为四个级别,以评估制药公司的增长趋势。