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帕金森病抑郁症的远程健康跨诊断认知行为疗法:一项初步随机对照试验。

Telehealth Transdiagnostic Cognitive Behavioral Therapy for Depression in Parkinson's Disease: A Pilot Randomized Controlled Trial.

作者信息

Piers Ryan J, Farchione Todd J, Wong Bonnie, Rosellini Anthony J, Cronin-Golomb Alice

机构信息

Department of Psychological and Brain Sciences Boston University Boston Massachusetts USA.

Department of Psychiatry Massachusetts General Hospital Charlestown Massachusetts USA.

出版信息

Mov Disord Clin Pract. 2022 Oct 29;10(1):79-85. doi: 10.1002/mdc3.13587. eCollection 2023 Jan.

Abstract

BACKGROUND

Cognitive behavioral therapy (CBT) is an effective treatment for depression in persons with Parkinson's disease (PwPD), but there are significant barriers preventing PwPD from receiving care in person. Telehealth CBT circumvents many of these barriers.

OBJECTIVES

We conducted a pilot randomized controlled trial evaluating the efficacy, feasibility, and acceptability of telehealth transdiagnostic CBT intervention for depression in PwPD.

METHODS

Twelve PwPD with Major Depressive Disorder were enrolled, half randomly assigned to the treatment-immediate condition (TI) and half to the waitlist control condition (WLC). TI and WLC participants received 12 CBT sessions and assessments before treatment, immediately after treatment, and at the 6-week follow-up.

RESULTS

The intervention was efficacious for treating depression in PwPD, with secondary benefits to anxiety, apathy, learning, memory, and quality of life. Improvements were largely maintained at follow-up. The intervention was highly feasible and acceptable.

CONCLUSIONS

Telehealth transdiagnostic CBT was an effective intervention for PwPD with depression.

摘要

背景

认知行为疗法(CBT)是治疗帕金森病患者(PwPD)抑郁症的有效方法,但存在重大障碍,阻碍PwPD接受面对面护理。远程医疗CBT规避了其中许多障碍。

目的

我们进行了一项试点随机对照试验,评估远程医疗跨诊断CBT干预对PwPD抑郁症的疗效、可行性和可接受性。

方法

招募了12名患有重度抑郁症的PwPD,一半随机分配到立即治疗组(TI),另一半分配到等待名单对照组(WLC)。TI组和WLC组参与者在治疗前、治疗后立即以及6周随访时接受了12次CBT治疗和评估。

结果

该干预对治疗PwPD抑郁症有效,对焦虑、冷漠、学习、记忆和生活质量有次要益处。随访时改善情况基本维持。该干预具有高度可行性和可接受性。

结论

远程医疗跨诊断CBT是治疗PwPD抑郁症的有效干预措施。

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