Niijima K H, Yonekawa Y, Taki W, Handa H, Ikada Y
Department of Neurosurgery, National Cardiovascular Center, Osaka, Japan.
No Shinkei Geka. 1987 Jun;15(6):625-32.
Sutureless end-to-end anastomosis of rat common carotid artery was carried out, low energy Nd-YAG laser being used thereby. An intraluminal-intervascular splint, made of water-soluble poval, was used for precise adaptation of the intimas. Neither stay suture nor glue was required. The patency rate of the anastomosed vessels, 24 hours after operation, was as high as 91%. The vessels were confirmed to be likewise patent on the 7th and 30th postoperative day. Complications such as pseudoaneurysm formation or stenotic change, were negligible. The fusion of the anastomosis with Nd-YAG laser was histologically proved to be satisfactory and the result of tensile strength test was excellent. Temperature at the anastomotic site during laser irradiation was measured, optimal energy for anastomosis determined and possible mechanism of vascular fusion by laser beam postulated. The major advantages of the laser technique combined with poval splint, such as rapidity, consistency and no residual foreign body (thread or adhesive), are discussed.
采用低能量钕钇铝石榴石激光对大鼠颈总动脉进行无缝合端端吻合术。使用由水溶性聚乙烯醇制成的腔内血管间夹板，以精确适配内膜。既不需要留置缝线也不需要胶水。术后24小时吻合血管的通畅率高达91%。在术后第7天和第30天，血管同样被证实通畅。诸如假性动脉瘤形成或狭窄改变等并发症可忽略不计。组织学证明钕钇铝石榴石激光吻合融合效果良好，拉伸强度测试结果优异。测量了激光照射期间吻合部位的温度，确定了吻合的最佳能量，并推测了激光束血管融合的可能机制。讨论了激光技术结合聚乙烯醇夹板的主要优点，如快速、一致性好且无残留异物（线或粘合剂）。
