Bousquet Jean, Anto Josep M, Sousa-Pinto Bernardo, Czarlewski Wienczyslawa, Bedbrook Anna, Haahtela Tari, Klimek Ludger, Pfaar Oliver, Kuna Piotr, Kupczyk Maciej, Regateiro Frederico S, Samolinski Boleslaw, Valiulis Arunas, Yorgancioglu Arzu, Arnavielhe Sylvie, Basagaña Xavier, Bergmann Karl C, Bosnic-Anticevich Sinthia, Brussino Luisa, Canonica G Walter, Cardona Victoria, Cecchi Lorenzo, Chaves-Loureiro Claudia, Costa Elisio, Cruz Alvaro A, Gemicioglu Bilun, Fokkens Wytske J, Ivancevich Juan Carlos, Kraxner Helga, Kvedariene Violeta, Larenas-Linnemann Désirée E, Laune Daniel, Louis Renaud, Makris Michael, Maurer Marcus, Melén Erik, Micheli Yann, Morais-Almeida Mario, Mullol Joaquim, Niedoszytko Marek, Okamoto Yoshitaka, Papadopoulos Nikolaos G, Patella Vincenzo, Pham-Thi Nhân, Rouadi Philip W, Sastre Joaquin, Scichilone Nicola, Sheikh Aziz, Sofiev Mikhail, Taborda-Barata Luis, Toppila-Salmi Sanna, Tsiligianni Ioanna, Valovirta Erkka, Ventura Maria Teresa, Vieira Rafael José, Zidarn Mihaela, Amaral Rita, Ansotegui Ignacio J, Bédard Annabelle, Benveniste Samuel, Bewick Michael, Bindslev-Jensen Carsten, Blain Hubert, Bonini Matteo, Bourret Rodolphe, Braido Fulvio, Carreiro-Martins Pedro, Charpin Denis, Cherrez-Ojeda Ivan, Chivato Tomas, Chu Derek K, Cingi Cemal, Del Giacco Stefano, de Blay Frédéric, Devillier Philippe, De Vries Govert, Doulaptsi Maria, Doyen Virginie, Dray Gérard, Fontaine Jean-François, Gomez R Maximiliano, Hagemann Jan, Heffler Enrico, Hofmann Maja, Jassem Ewa, Jutel Marek, Keil Thomas, Kritikos Vicky, Kull Inger, Kulus Marek, Lourenço Olga, Mathieu-Dupas Eve, Menditto Enrica, Mösges Ralph, Murray Ruth, Nadif Rachel, Neffen Hugo, Nicola Stefania, O'Hehir Robyn, Olze Heidi, Palamarchuk Yuliia, Pépin Jean-Louis, Pétré Benoit, Picard Robert, Pitsios Constantinos, Puggioni Francesca, Quirce Santiago, Raciborski Filip, Reitsma Sietze, Roche Nicolas, Rodriguez-Gonzalez Monica, Romantowski Jan, Sá-Sousa Ana, Serpa Faradiba S, Savouré Marine, Shamji Mohamed H, Sova Milan, Sperl Annette, Stellato Cristiana, Todo-Bom Ana, Tomazic Peter Valentin, Vandenplas Olivier, Van Eerd Michiel, Vasankari Tuula, Viart Frédéric, Waserman Susan, Fonseca Joao A, Zuberbier Torsten
Institute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Berlin, Germany.
Clin Transl Allergy. 2023 Jan;13(1):e12215. doi: 10.1002/clt2.12215.
MASK-air , a validated mHealth app (Medical Device regulation Class IIa) has enabled large observational implementation studies in over 58,000 people with allergic rhinitis and/or asthma. It can help to address unmet patient needs in rhinitis and asthma care. MASK-air is a Good Practice of DG Santé on digitally-enabled, patient-centred care. It is also a candidate Good Practice of OECD (Organisation for Economic Co-operation and Development). MASK-air data has enabled novel phenotype discovery and characterisation, as well as novel insights into the management of allergic rhinitis. MASK-air data show that most rhinitis patients (i) are not adherent and do not follow guidelines, (ii) use as-needed treatment, (iii) do not take medication when they are well, (iv) increase their treatment based on symptoms and (v) do not use the recommended treatment. The data also show that control (symptoms, work productivity, educational performance) is not always improved by medications. A combined symptom-medication score (ARIA-EAACI-CSMS) has been validated for clinical practice and trials. The implications of the novel MASK-air results should lead to change management in rhinitis and asthma.
MASK-air是一款经过验证的移动健康应用程序（医疗器械法规IIa类），已在超过58000名过敏性鼻炎和/或哮喘患者中开展了大规模观察性实施研究。它有助于满足鼻炎和哮喘护理中未得到满足的患者需求。MASK-air是欧盟卫生与食品安全总司关于数字化、以患者为中心护理的良好实践。它也是经济合作与发展组织（经合组织）的候选良好实践。MASK-air数据有助于发现和表征新的表型，以及对过敏性鼻炎管理有新的见解。MASK-air数据显示，大多数鼻炎患者：（i）不依从且不遵循指南，（ii）按需治疗，（iii）病情好转时不服药，（iv）根据症状增加治疗，（v）不使用推荐治疗。数据还表明，药物治疗并不总能改善控制情况（症状、工作效率、学习成绩）。一种综合症状-药物评分（ARIA-EAACI-CSMS）已在临床实践和试验中得到验证。MASK-air新结果的影响应会导致鼻炎和哮喘的管理变革。
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