Suppr超能文献

血管栓塞术与开放性探查术治疗中重度钝性肝损伤对死亡率的影响

The Effect of Angioembolization Versus Open Exploration for Moderate to Severe Blunt Liver Injuries on Mortality.

作者信息

Gallaher Jared, Burton Victoria, Schneider Andrew B, Reid Trista, Raff Lauren, Smith Charlotte B, Charles Anthony

机构信息

Division of Trauma and Acute Care Surgery, Department of Surgery, University of North Carolina at Chapel Hill, 4006 Burnett Womack Building, Chapel Hill, NC, 27599-7228, USA.

出版信息

World J Surg. 2023 May;47(5):1271-1281. doi: 10.1007/s00268-023-06926-5. Epub 2023 Jan 27.

Abstract

INTRODUCTION

Blunt liver injury is common and is associated with a high morbidity and mortality. More severe injuries often require either angioembolization or open operative repair, depending on patient factors and facility capacity. We sought to describe patient outcomes based on intervention type.

METHODS

We analyzed the National Trauma Data Bank (2017-2019) using ICD-10 codes to identify adult patients with blunt liver injury and their interventions. AIS (Abbreviated Injury Scale) scores were used to group patients based on liver injury severity (AIS 2-6). Logistic regression modeling was used to estimate the adjusted odds ratio of death based on intervention type, excluding patients with severe injury.

RESULTS

Of 2,848,592 trauma patients, 50,250 patients had a blunt liver injury. Among patients with AIS 3/4/5 injury, 1,140 had angioembolization, 1,529 had an open repair, and 188 had both angioembolization and open repair. In comparison with no intervention and adjusted for age, sex, shock index, ISS, and transfusion total (first four hours), angioembolization was associated with a significant decrease in the odds of mortality for patients with an AIS 4 (OR 0.68, 95% CI 0.47, 0.99) and AIS 5 injury (OR 0.39, 95% CI 0.24, 0.64). In patients with an AIS 5 injury, open repair had an increased odds of mortality at OR 1.99 (95% CI 1.47, 2.69).

CONCLUSION

In an analysis of a national trauma database, patients with a moderate to severe injury (AIS 4 or 5), angioembolization was associated with a significant reduction in the adjusted odds of mortality compared to open repair and should be considered when clinically appropriate.

摘要

引言

钝性肝损伤很常见,且与高发病率和死亡率相关。更严重的损伤通常需要根据患者因素和医疗机构的能力,进行血管栓塞或开放手术修复。我们试图根据干预类型描述患者的预后情况。

方法

我们使用国际疾病分类第十版(ICD - 10)编码分析了国家创伤数据库(2017 - 2019年),以识别患有钝性肝损伤的成年患者及其所接受的干预措施。简明损伤定级(AIS)评分用于根据肝损伤严重程度(AIS 2 - 6)对患者进行分组。逻辑回归模型用于估计基于干预类型的调整后死亡比值比,排除重伤患者。

结果

在2848592例创伤患者中,50250例患有钝性肝损伤。在AIS 3/4/5级损伤的患者中,1140例接受了血管栓塞治疗,1529例接受了开放修复手术,188例同时接受了血管栓塞和开放修复手术。与未进行干预相比,并对年龄、性别、休克指数、损伤严重度评分(ISS)和输血总量(最初四小时)进行调整后,血管栓塞与AIS 4级(比值比0.68,95%置信区间0.47,0.99)和AIS 5级损伤(比值比0.39,95%置信区间0.24,0.64)患者的死亡几率显著降低相关。在AIS 5级损伤的患者中,开放修复的死亡几率增加,比值比为1.99(95%置信区间1.47,2.69)。

结论

在对国家创伤数据库的分析中,对于中度至重度损伤(AIS 4或5)的患者,与开放修复相比,血管栓塞与调整后的死亡几率显著降低相关,在临床合适时应予以考虑。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验