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创伤性休克指数对钝性胸部创伤患者干预和死亡率的预测价值。

Shock Index for the Prediction of Interventions and Mortality in Patients With Blunt Thoracic Trauma.

机构信息

Clinical Research, Trauma & Vascular Surgery, Hamad General Hospital, Doha, Qatar.

Clinical Research, Trauma & Vascular Surgery, Hamad General Hospital, Doha, Qatar; Clinical Medicine, Weill Cornell Medical College, Doha, Qatar.

出版信息

J Surg Res. 2023 Mar;283:438-448. doi: 10.1016/j.jss.2022.10.067. Epub 2022 Nov 23.

Abstract

INTRODUCTION

Shock index (SI) is a bedside simple scoring tool; however, it has not yet been tested in blunt thorax trauma (BTT). We sought to evaluate the prognostic value of SI for chest interventions (thoracostomy tube or thoracotomy), blood transfusion, and mortality in patients with BTT. We hypothesized that high SI is associated with worse outcomes in patients with BTT.

METHODS

We conducted a retrospective analysis of all BTT patients (chest Abbreviated Injury Score [AIS] > 1) hospitalized in a level 1 trauma center between 2011 and 2020. Patients with AIS >1 for head or abdominal injuries and patients undergoing open reduction and internal fixation surgery or penetrating injuries were excluded. Patients were categorized into two groups (low SI <0.80 versus high SI ≥0.80) based on the receiver operating characteristic curve analysis. Multivariable regression analysis was performed to identify the predictors of mortality.

RESULTS

A total of 1645 patients were admitted with BTT; of them, 24.5% had high SI. The mean age was 39.2 ± 15.2 y, and most were males (91%). Patients with high SI were younger, had sustained severer injuries, and required more chest interventions (P = 0.001), blood transfusion (P = 0.001), and massive transfusion protocol activation (P = 0.001) compared with low SI group. The overall in-hospital mortality rate was 2.6%, which was more in the high SI group (8.2% versus 0.8%; P = 0.001). SI significantly correlated with age (r = -0.281), injury severity score (r = 0.418), Glasgow Come Score on arrival (r = -0.377), Trauma and Injury Severity Score (r = -0.144), Revised Trauma Score (r = -0.219), serum lactate (r = 0.434), blood transfusion units (r = 0.418), and chest AIS (r = 0.066). SI was an independent predictor of mortality (odds ratio 3.506; 95% confidence interval 1.389-8.848; P = 0.008), and this effect persisted after adjustment for chest intervention (odds ratio 2.923; 95% confidence interval 1.146-7.455; P = 0.02).

CONCLUSIONS

The present study highlights the prognostic value of SI as a rapid bedside tool to predict the use of interventions and the risk of mortality in patients with BTT. The study findings help the emergency physicians for early and appropriate risk stratification and triaging of patients with BTT.

摘要

简介

休克指数(SI)是一种床边简单评分工具,但尚未在钝性胸部创伤(BTT)中进行测试。我们旨在评估 SI 对 BTT 患者进行胸部干预(胸腔引流管或开胸手术)、输血和死亡率的预后价值。我们假设高 SI 与 BTT 患者的不良预后相关。

方法

我们对 2011 年至 2020 年间在一级创伤中心住院的所有 BTT 患者(胸部简明损伤评分[Abbreviated Injury Score,AIS]>1)进行了回顾性分析。排除 AIS >1 用于头部或腹部损伤的患者,以及接受开放复位内固定手术或穿透性损伤的患者。根据受试者工作特征曲线分析,将患者分为两组(低 SI<0.80 与高 SI≥0.80)。采用多变量回归分析识别死亡率的预测因素。

结果

共 1645 例患者因 BTT 入院;其中 24.5% 的患者 SI 较高。平均年龄为 39.2±15.2 岁,大多数为男性(91%)。与低 SI 组相比,高 SI 组的患者更年轻,损伤更严重,需要更多的胸部干预(P=0.001)、输血(P=0.001)和大量输血方案激活(P=0.001)。总体住院死亡率为 2.6%,高 SI 组更高(8.2%比 0.8%;P=0.001)。SI 与年龄(r=-0.281)、损伤严重程度评分(r=0.418)、入院时格拉斯哥昏迷评分(r=-0.377)、创伤和损伤严重程度评分(r=-0.144)、修订创伤评分(r=-0.219)、血清乳酸(r=0.434)、输血单位(r=0.418)和胸部 AIS(r=0.066)显著相关。SI 是死亡率的独立预测因素(比值比 3.506;95%置信区间 1.389-8.848;P=0.008),并且这种影响在调整胸部干预后仍然存在(比值比 2.923;95%置信区间 1.146-7.455;P=0.02)。

结论

本研究强调了 SI 作为一种快速床边工具的预后价值,可预测 BTT 患者干预的使用和死亡率的风险。研究结果有助于急诊医生对 BTT 患者进行早期和适当的风险分层和分诊。

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