Abdi Khaoula, Ben Said Mourad, Crotti Elena, Masmoudi Ahmed Sleheddine, Cherif Ameur
Univ. Manouba, ISBST, BVBGR-LR11ES31, Biotechpole Sidi Thabet, 2020, Ariana, Tunisia.
Department of Basic Sciences, Higher Institute of Biotechnology of Sidi Thabet, University of Manouba, 2010, Manouba, Tunisia.
Arch Microbiol. 2023 Jan 27;205(2):73. doi: 10.1007/s00203-023-03416-z.
Over the last decades, losses of bee populations have been observed worldwide. A panoply of biotic and abiotic factors, as well as the interplay among them, has been suggested to be responsible for bee declines, but definitive causes have not yet been identified. Among pollinators, the honeybee Apis mellifera is threatened by various diseases and environmental stresses, which have been shown to impact the insect gut microbiota that is known to be fundamental for host metabolism, development and immunity. Aimed at preserving the gut homeostasis, many researches are currently focusing on improving the honeybee health through the administration of probiotics e.g., by boosting the innate immune response against microbial infections. Here, we review the knowledge available on the characterization of the microbial diversity associated to honeybees and the use of probiotic symbionts as a promising approach to maintain honeybee fitness, sustaining a healthy gut microbiota and enhancing its crucial relationship with the host immune system.
在过去几十年里，全球范围内都观察到了蜜蜂种群数量的减少。一系列生物和非生物因素，以及它们之间的相互作用，被认为是导致蜜蜂数量下降的原因，但确切原因尚未确定。在传粉者中，西方蜜蜂（Apis mellifera）受到各种疾病和环境压力的威胁，这些已被证明会影响昆虫肠道微生物群，而肠道微生物群对宿主的新陈代谢、发育和免疫至关重要。为了维持肠道内环境稳定，目前许多研究都集中在通过施用益生菌来改善蜜蜂健康，例如通过增强针对微生物感染的先天免疫反应。在这里，我们综述了与蜜蜂相关的微生物多样性特征以及使用益生菌共生体作为维持蜜蜂健康、维持健康肠道微生物群并加强其与宿主免疫系统关键关系的一种有前景方法的现有知识。
