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非结核分枝杆菌感染的环境风险:方法学的推进策略。

Environmental risk of nontuberculous mycobacterial infection: Strategies for advancing methodology.

机构信息

Division of Intramural Research, Epidemiology and Population Studies Unit, NIAID, NIH, Rockville, MD, USA.

Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA.

出版信息

Tuberculosis (Edinb). 2023 Mar;139:102305. doi: 10.1016/j.tube.2023.102305. Epub 2023 Jan 10.

Abstract

The National Institute of Allergy and Infectious Diseases organized a symposium in June 2022, to facilitate discussion of the environmental risks for nontuberculous mycobacteria exposure and disease. The expert researchers presented recent studies and identified numerous research gaps. This report summarizes the discussion and identifies six major areas of future research related to culture-based and culture independent laboratory methods, alternate culture media and culturing conditions, frameworks for standardized laboratory methods, improved environmental sampling strategies, validation of exposure measures, and availability of high-quality spatiotemporal data.

摘要

美国过敏和传染病研究所于 2022 年 6 月组织了一次研讨会,旨在促进对非结核分枝杆菌暴露和疾病的环境风险的讨论。专家研究人员介绍了最近的研究,并确定了许多研究空白。本报告总结了讨论内容,并确定了与基于培养和非培养实验室方法、替代培养介质和培养条件、标准化实验室方法框架、改进的环境采样策略、暴露措施的验证以及高质量时空数据的可用性相关的六个主要研究领域。

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