Mohottige Dinushika, Olabisi Opeyemi, Boulware L Ebony
Division of Nephrology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA; email:
Center for Community and Population Health Improvement, Clinical and Translational Science Institute, Duke University School of Medicine, Durham, North Carolina, USA.
Annu Rev Med. 2023 Jan 27;74:385-400. doi: 10.1146/annurev-med-042921-124419.
In 2020, the nephrology community formally interrogated long-standing race-based clinical algorithms used in the field, including the kidney function estimation equations. A comprehensive understanding of the history of kidney function estimation and racial essentialism is necessary to understand underpinnings of the incorporation of a Black race coefficient into prior equations. We provide a review of this history, as well as the considerations used to develop race-free equations that are a guidepost for a more equity-oriented, scientifically rigorous future for kidney function estimation and other clinical algorithms and processes in which race may be embedded as a variable.
2020年,肾脏病学界正式审视了该领域长期使用的基于种族的临床算法,包括肾功能估算方程。要理解在先前方程中纳入黑人种族系数的基础,有必要全面了解肾功能估算的历史和种族本质主义。我们回顾了这段历史,以及用于开发无种族方程的考量因素,这些方程为肾功能估算以及其他可能将种族作为变量纳入其中的临床算法和流程,朝着更公平、科学严谨的未来发展提供了指导。