Lockner D
Acta Med Scand. 1979;205(1-2):97-101. doi: 10.1111/j.0954-6820.1979.tb06010.x.
A therapeutic trial with methenolone (Primobolan) in 19 consecutive patients with different types of refractory anemia is reported. The remission frequencies were: pancytopenia 3/6, bicytopenia 2/4, refractory anemia with hyperplastic marrow 1/5, myelofibrosis 1/4. There was no obvious prolongation of survival in the patients responding. Side-effects were negligible.
报告了对19例不同类型难治性贫血患者使用美睾酮(普丽莫宝)的治疗试验。缓解频率如下:全血细胞减少症3/6,二系血细胞减少症2/4,骨髓增生性难治性贫血1/5,骨髓纤维化1/4。有反应的患者生存期无明显延长。副作用可忽略不计。