Girot R, Pecking A, Najean Y
Arch Fr Pediatr. 1976 Oct;33(8):761-9.
The preliminary results of a prospective study of androgen therapy in the treatment of bone marrow insufficiency in children are reported. This study includes 11 children with the Fanconi syndrome, 21 idiopathic and 3 with toxic aplastic anaemia. Nine patients died early in the course of treatment. Impaired liver function was observed in 28% of patients and virilization in 37% of patients.
报告了一项关于雄激素治疗儿童骨髓功能不全的前瞻性研究的初步结果。该研究包括11名患有范可尼综合征的儿童、21名特发性患者和3名中毒性再生障碍性贫血患者。9名患者在治疗过程早期死亡。28%的患者观察到肝功能受损,37%的患者出现男性化。