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[Chinese expert consensus of allogeneic hematopoietic stem cell transplantation for pediatric acute lymphoblastic leukemia (2022)].

出版信息

Zhonghua Xue Ye Xue Za Zhi. 2022 Oct 14;43(10):793-801. doi: 10.3760/cma.j.issn.0253-2727.2022.10.001.

DOI:10.3760/cma.j.issn.0253-2727.2022.10.001
PMID:36709192
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9669632/
Abstract
摘要

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Efficacy and safety of CD19-specific CAR T cell-based therapy in B-cell acute lymphoblastic leukemia patients with CNSL.基于CD19特异性嵌合抗原受体T细胞疗法在伴中枢神经系统白血病的B细胞急性淋巴细胞白血病患者中的疗效与安全性
Blood. 2022 Jun 9;139(23):3376-3386. doi: 10.1182/blood.2021013733.
2
Chimeric Antigens Receptor T Cell Therapy Improve the Prognosis of Pediatric Acute Lymphoblastic Leukemia With Persistent/Recurrent Minimal Residual Disease in First Complete Remission.嵌合抗原受体 T 细胞疗法改善首次完全缓解时持续/复发微小残留病的儿童急性淋巴细胞白血病的预后。
Front Immunol. 2022 Jan 7;12:731435. doi: 10.3389/fimmu.2021.731435. eCollection 2021.
3
Total Body Irradiation Forever? Optimising Chemotherapeutic Options for Irradiation-Free Conditioning for Paediatric Acute Lymphoblastic Leukaemia.全身照射会一直存在吗？优化小儿急性淋巴细胞白血病无照射预处理的化疗方案。
Front Pediatr. 2021 Dec 10;9:775485. doi: 10.3389/fped.2021.775485. eCollection 2021.
4
Results of a multicenter phase I/II trial of TCRαβ and CD19-depleted haploidentical hematopoietic stem cell transplantation for adult and pediatric patients.一项多中心 I/II 期临床试验的结果：TCRαβ 和 CD19 耗竭的单倍体相合造血干细胞移植治疗成人和儿童患者。
Bone Marrow Transplant. 2022 Mar;57(3):423-430. doi: 10.1038/s41409-021-01551-z. Epub 2021 Dec 24.
5
Clinical pharmacology of cytotoxic drugs in neonates and infants: Providing evidence-based dosing guidance.新生儿和婴儿细胞毒药物的临床药理学：提供基于证据的剂量指导。
Eur J Cancer. 2022 Mar;164:137-154. doi: 10.1016/j.ejca.2021.11.001. Epub 2021 Dec 2.
6
The consensus from The Chinese Society of Hematology on indications, conditioning regimens and donor selection for allogeneic hematopoietic stem cell transplantation: 2021 update.中华血液学分会关于异基因造血干细胞移植适应证、预处理方案及供者选择的专家共识（2021 年版）
J Hematol Oncol. 2021 Sep 15;14(1):145. doi: 10.1186/s13045-021-01159-2.
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Preemptive donor-derived anti-CD19 CAR T-cell infusion showed a promising anti-leukemia effect against relapse in MRD-positive B-ALL after allogeneic hematopoietic stem cell transplantation.抢先输注供体来源的抗CD19嵌合抗原受体T细胞，对异基因造血干细胞移植后微小残留病阳性的B淋巴细胞白血病复发显示出有前景的抗白血病效果。
Leukemia. 2022 Jan;36(1):267-270. doi: 10.1038/s41375-021-01351-w. Epub 2021 Jul 20.
8
Unmanipulated haploidentical hematopoietic stem cell transplantation is an excellent option for children and young adult relapsed/refractory Philadelphia chromosome-negative B-cell acute lymphoblastic leukemia after CAR-T-cell therapy.未处理的单倍体相合造血干细胞移植是 CAR-T 细胞治疗后复发/难治性费城染色体阴性 B 细胞急性淋巴细胞白血病儿童和年轻成人的绝佳选择。
Leukemia. 2021 Nov;35(11):3092-3100. doi: 10.1038/s41375-021-01236-y. Epub 2021 Apr 6.
9
Effect of Blinatumomab vs Chemotherapy on Event-Free Survival Among Children With High-risk First-Relapse B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial.Blinatumomab 与化疗治疗高危初发 B 细胞急性淋巴细胞白血病患儿无事件生存的效果：一项随机临床试验。
JAMA. 2021 Mar 2;325(9):843-854. doi: 10.1001/jama.2021.0987.
10
Re-Emergence of Minimal Residual Disease Detected by Flow Cytometry Predicts an Adverse Outcome in Pediatric Acute Lymphoblastic Leukemia.通过流式细胞术检测到的微小残留病再次出现预示着儿童急性淋巴细胞白血病的不良预后。
Front Oncol. 2021 Feb 5;10:596677. doi: 10.3389/fonc.2020.596677. eCollection 2020.