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Outcome prediction in myelodysplastic neoplasm undergoing hematopoietic cell transplant in the molecular era of IPSS-M.

作者信息

Gurnari Carmelo, Gagelmann Nico, Badbaran Anita, Awada Hussein, Dima Danai, Pagliuca Simona, D'Aveni-Piney Maud, Attardi Enrico, Voso Maria Teresa, Cerretti Raffaella, Wolschke Christine, Rubio Marie Thérèse, Maciejewski Jaroslaw P, Kröger Nicolaus

机构信息

Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.

Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.

出版信息

Leukemia. 2023 Mar;37(3):717-719. doi: 10.1038/s41375-023-01820-4. Epub 2023 Jan 28.

DOI:10.1038/s41375-023-01820-4
PMID:36709353
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11104020/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a622/11104020/e43bfa072e20/nihms-1962633-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a622/11104020/e43bfa072e20/nihms-1962633-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a622/11104020/e43bfa072e20/nihms-1962633-f0001.jpg

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本文引用的文献

1
Molecular International Prognostic Scoring System for Myelodysplastic Syndromes.骨髓增生异常综合征的分子国际预后评分系统
NEJM Evid. 2022 Jul;1(7):EVIDoa2200008. doi: 10.1056/EVIDoa2200008. Epub 2022 Jun 12.
2
Clinical and Molecular Determinants of Clonal Evolution in Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria.再生障碍性贫血和阵发性睡眠性血红蛋白尿症中克隆进化的临床和分子决定因素。
J Clin Oncol. 2023 Jan 1;41(1):132-142. doi: 10.1200/JCO.22.00710. Epub 2022 Sep 2.
3
Have we reached a molecular era in myelodysplastic syndromes?
慢性粒单核细胞白血病的异基因移植
Curr Hematol Malig Rep. 2025 Aug 11;20(1):10. doi: 10.1007/s11899-025-00754-1.
4
IPSS-M outperforms IPSS-R in prognostic stratification and guides effective interventions for very High-Risk myelodysplastic syndrome patients undergoing allogeneic hematopoietic stem cell transplantation.国际预后评分系统-骨髓(IPSS-M)在预后分层方面优于国际预后评分系统-修订版(IPSS-R),并为接受异基因造血干细胞移植的极高危骨髓增生异常综合征患者指导有效的干预措施。
Discov Oncol. 2025 Jul 11;16(1):1315. doi: 10.1007/s12672-025-03155-1.
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Threefold IPSS-M reclassification outperforms original stratification in predicting post-transplant outcomes for MDS patients.在预测骨髓增生异常综合征(MDS)患者移植后结局方面,IPSS-M三分法重新分类优于原始分层。
Cell Transplant. 2025 Jan-Dec;34:9636897251348406. doi: 10.1177/09636897251348406. Epub 2025 Jun 24.
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Advances and challenges in the treatment of myelodysplastic syndromes.骨髓增生异常综合征治疗的进展与挑战
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8
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Ann Hematol. 2025 Jan;104(1):193-206. doi: 10.1007/s00277-024-06162-4. Epub 2024 Dec 30.
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Haematologica. 2025 Feb 1;110(2):339-349. doi: 10.3324/haematol.2023.284946.
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Semin Hematol. 2024 Dec;61(6):420-430. doi: 10.1053/j.seminhematol.2024.10.004. Epub 2024 Oct 17.
我们是否已经进入骨髓增生异常综合征的分子时代?
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Myelodysplastic syndromes: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.骨髓增生异常综合征:ESMO诊断、治疗及随访临床实践指南
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Biol Blood Marrow Transplant. 2020 Mar;26(3):451-457. doi: 10.1016/j.bbmt.2019.10.015. Epub 2019 Oct 21.
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Optimized EBMT transplant-specific risk score in myelodysplastic syndromes after allogeneic stem-cell transplantation.异基因造血干细胞移植后骨髓增生异常综合征的改良 EBMT 移植特异性风险评分。
Haematologica. 2019 May;104(5):929-936. doi: 10.3324/haematol.2018.200808. Epub 2019 Jan 17.
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Genetic abnormalities in myelodysplasia and secondary acute myeloid leukemia: impact on outcome of stem cell transplantation.骨髓增生异常综合征和继发性急性髓系白血病中的基因异常:对干细胞移植结果的影响。
Blood. 2017 Apr 27;129(17):2347-2358. doi: 10.1182/blood-2016-12-754796. Epub 2017 Feb 21.
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Prognostic Mutations in Myelodysplastic Syndrome after Stem-Cell Transplantation.干细胞移植后骨髓增生异常综合征的预后性突变
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