Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing, China.
Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China.
Sci Rep. 2023 Jan 28;13(1):1586. doi: 10.1038/s41598-023-28758-y.
Skin blood flux (SkBF) changes caused by drinking cold water are generally associated with vagal tone and osmotic factors in the digestive system. However, there is still a lack of relevant research on whether there are left and right differences in these SkBF change. In the current study, a total of 60 subjects were recruited. Skin blood perfusion of the bilateral lower extremities was recorded simultaneously before and after drinking saline of different temperatures saline by using Laser Doppler flowmetry (LDF). The electrogastrogram (EGG) was also monitored, and the dominant frequency of the EGG and heart rate variability were analyzed. The results indicated that after drinking saline, the laterality index of SkBF at the lower extremities was different and the laterality index changes of SkBF were mainly reflected in the frequency interval V (0.4-1.6 Hz). There was a weak negative correlation between the laterality index of endothelial NO-dependent component and change rate of root mean square of successive differences (RMSSD) after drinking 4 °C saline. However, after drinking 30 °C saline, there was a weak positive correlation between neurogenic component and RMSSD The distribution and regulation of bilateral blood flow are not symmetrical but exhibit a certain laterality.
饮用冷水引起的皮肤血流（SkBF）变化通常与迷走神经张力和消化系统中的渗透因素有关。然而，对于这些 SkBF 变化是否存在左右差异，相关研究仍然缺乏。在目前的研究中，共招募了 60 名受试者。通过激光多普勒血流仪（LDF）在饮用不同温度盐水前后同步记录双侧下肢皮肤血流灌注情况，并监测胃电图（EGG），分析 EGG 的主导频率和心率变异性。结果表明，饮用盐水后，下肢 SkBF 的侧支指数存在差异，SkBF 侧支指数的变化主要反映在频带 V（0.4-1.6 Hz）。饮用 4°C 盐水后，内皮一氧化氮依赖性成分的侧支指数与连续差均方根（RMSSD）变化率呈弱负相关。然而，饮用 30°C 盐水后，神经源性成分与 RMSSD 呈弱正相关。双侧血流的分布和调节不是对称的，而是表现出一定的侧支性。
