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创伤性休克患者主动脉内复苏球囊阻断术的可行性及临床结果:单中心5年经验

Feasibility and Clinical Outcomes of Resuscitative Endovascular Balloon Occlusion of the Aorta in Patients with Traumatic Shock: A Single-Center 5-Year Experience.

作者信息

Lee Gyeongho, Kim Dong Hun, Ma Dae Sung, Lee Seok Won, Heo Yoonjung, Jo Hancheol, Chang Sung Wook

机构信息

Department of Thoracic and Cardiovascular Surgery, Dankook University Hospital, Cheonan, Korea.

Department of Trauma Surgery, Trauma Center, Dankook University Hospital, Cheonan, Korea.

出版信息

J Chest Surg. 2023 Mar 5;56(2):108-116. doi: 10.5090/jcs.22.105. Epub 2023 Jan 30.

Abstract

BACKGROUND

Resuscitative endovascular balloon occlusion of the aorta (REBOA) has recently gained popularity as an adjunct to resuscitation of patients with traumatic shock. However, the effectiveness of REBOA is still debated because of inconsistent indications across centers and the lack of medical records. The purpose of this study was to investigate the effectiveness and feasibility of REBOA by analyzing clinical results from a single center.

METHODS

This study included 96 patients who underwent REBOA between August 2016 and September 2021 at a regional trauma center according to the center's treatment algorithm for traumatic shock. Medical records, including the time of the decision to conduct the REBOA procedure, time of operation, type of aortic occlusion, and clinical outcomes, were collected prospectively and analyzed retrospectively. Patients were classified by REBOA protocol (group 1, 2, or 3) and survival status (survivor or non-survivor) for analysis.

RESULTS

The overall success rate of the procedure was 97.9%, and the survival rate was 32.6%. In survivors, blood pressure was higher than in non-survivors both before the REBOA procedure (p=0.002) and after aortic occlusion (p=0.03). The total aortic occlusion time was significantly shorter (p=0.001) and the proportion of partial aortic occlusion was significantly higher (p=0.014) among the survivors. The non-survivors had more acidosis (p<0.001) and higher lactate concentrations (p<0.001) than the survivors.

CONCLUSION

REBOA may be a feasible bridge therapy for resuscitation of patients with traumatic shock. Prompt and accurate decision-making to perform REBOA followed by damage control surgery could improve survival rates and clinical outcomes.

摘要

背景

复苏性血管内主动脉球囊阻断术(REBOA)作为创伤性休克患者复苏的辅助手段,近来受到广泛关注。然而,由于各中心适应证不一致且缺乏医疗记录,REBOA的有效性仍存在争议。本研究旨在通过分析单中心的临床结果,探讨REBOA的有效性和可行性。

方法

本研究纳入了96例于2016年8月至2021年9月期间在某地区创伤中心接受REBOA治疗的患者,这些患者均按照该中心创伤性休克的治疗方案进行治疗。前瞻性收集并回顾性分析医疗记录,包括决定进行REBOA手术的时间、手术时间、主动脉阻断类型及临床结局。根据REBOA方案(1组、2组或3组)和生存状态(存活者或非存活者)对患者进行分类分析。

结果

该手术的总体成功率为97.9%,生存率为32.6%。在存活者中,REBOA手术前(p=0.002)和主动脉阻断后(p=0.03)的血压均高于非存活者。存活者的主动脉总阻断时间明显更短(p=0.001),部分主动脉阻断的比例明显更高(p=0.014)。非存活者比存活者有更多的酸中毒(p<0.001)和更高的乳酸浓度(p<0.001)。

结论

REBOA可能是创伤性休克患者复苏的一种可行的桥梁治疗方法。迅速而准确地决定进行REBOA并随后进行损伤控制手术可提高生存率和临床结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c86/10008360/1e55cbc2fcfc/jcs-56-2-108-f1.jpg

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