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主动脉复苏性血管内球囊阻断术:文献综述及其在兽医急诊与重症监护中的应用

Resuscitative Endovascular Balloon Occlusion of the Aorta: Review of the Literature and Applications to Veterinary Emergency and Critical Care.

作者信息

Hoareau Guillaume L, Tibbits Emily M, Beyer Carl A, Simon Meryl A, DeSoucy Erik S, Faulconer E Robert, Neff Lucas P, Grayson J Kevin, Stewart Ian J, Williams Timothy K, Johnson M Austin

机构信息

Clinical Investigation Facility, David Grant USAF Medical Center, Travis Air Force Base, Travis, CA, United States.

Department of Surgery, University of California Davis Medical Center, Sacramento, CA, United States.

出版信息

Front Vet Sci. 2019 Jun 19;6:197. doi: 10.3389/fvets.2019.00197. eCollection 2019.

Abstract

While hemorrhagic shock might be the result of various conditions, hemorrhage control and resuscitation are the corner stone of patient management. Hemorrhage control can prove challenging in both the acute care and surgical settings, especially in the abdomen, where no direct pressure can be applied onto the source of bleeding. Resuscitative endovascular balloon occlusion of the aorta (REBOA) has emerged as a promising replacement to resuscitative thoracotomy (RT) for the management of non-compressible torso hemorrhage in human trauma patients. By inflating a balloon at specific levels (or zones) of the aorta to interrupt blood flow, hemorrhage below the level of the balloon can be controlled. While REBOA allows for hemorrhage control and augmentation of blood pressure cranial to the balloon, it also exposes caudal tissue beds to ischemia and the whole body to reperfusion injury. We aim to introduce the advantages of REBOA while reviewing known limitations. This review outlines a step-by-step approach to REBOA implementation, and discusses common challenges observed both in human patients and during translational large animal studies. Currently accepted and debated indications for REBOA in humans are discussed. Finally, we review possible applications for veterinary patients and how REBOA has the potential to be translated into clinical veterinary practice.

摘要

虽然失血性休克可能由多种情况引起,但出血控制和复苏是患者管理的基石。在急性护理和手术环境中,出血控制可能具有挑战性,尤其是在腹部,因为无法对出血源直接施加压力。复苏性血管内主动脉球囊阻断术(REBOA)已成为一种有前景的替代复苏性开胸术(RT)的方法,用于治疗人类创伤患者不可压缩的躯干出血。通过在主动脉的特定水平(或区域)充气球囊以中断血流,可以控制球囊水平以下的出血。虽然REBOA可以控制出血并提高球囊上方的血压,但它也会使尾部组织床暴露于缺血状态,并使全身暴露于再灌注损伤。我们旨在介绍REBOA的优点,同时回顾已知的局限性。本综述概述了实施REBOA的逐步方法,并讨论了在人类患者和转化性大型动物研究中观察到的常见挑战。讨论了目前在人类中接受和有争议的REBOA适应症。最后,我们回顾了兽医患者的可能应用,以及REBOA如何有可能转化为临床兽医实践。

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