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喀麦隆创伤病例中创伤性脑损伤的人口统计学、病因及结局:一项多中心五年回顾性研究

Demographics, Causes, and Outcome of Traumatic Brain Injury among Trauma Cases in Cameroon: A Multi-Center Five Year's Retrospective Study.

作者信息

Buh Franklin Chu, Taiwe Germain Sotoing, Maas Andrew I R, Motah Mathieu, Youm Eric, Wanyu Bertrand Yuwong, Wang Kevin W, Hutchinson Peter J A, Sumbele Irene Ule Ngole

机构信息

Department of Animal Biology and Conservation, Faculty of Science, University of Buea, Buea, Cameroon.

Panafrican Hospital Center-Douala, Buea, Cameroon.

出版信息

Neurotrauma Rep. 2022 Dec 26;3(1):569-583. doi: 10.1089/neur.2022.0053. eCollection 2022.

Abstract

Traumatic brain injury (TBI) is a huge public health challenge worldwide. Epidemiological monitoring is important to inform healthcare policy. We aimed at determining the prevalence, outcome, and causes of TBI in Cameroon by conducting a 5-year retrospective study in three referral trauma centers. Data on demographics, causes, injury mechanisms, clinical aspects, and discharge status were recorded. Comparisons between two categorical variables were done using Pearson's chi-square test or Fisher's exact test. A total of 6248 cases of TBI were identified of 18,151 trauma cases, yielding a prevalence of 34%. The number of TBI cases increased across the years (915 in 2016, 1406 in 2020). Demographic data and causes of TBI were available for 6248 subjects and detailed data on clinical characteristics on 2178 subjects. Median age was 30.0 (24.0, 41.0) years. Males were more affected (80%). Road traffic incidents (RTIs; 75%) was the main cause of TBI, with professional bike riders being more affected (17%). Computed tomography (CT) imaging was performed in 67.7% of cases. Of the 597 (27.4%) cases who did not undergo neuroimaging, 311 (52.1%) did not have neuroimaging performed because of financial constraints, among which 7% were severe TBI cases. A total of 341 (19.6%) patients were discharged against medical advice, of which 83% had financial limitations. Mortality was 10.3% (225 of 2178) in the overall population, but disproportionately high in patients with severe TBI (55%) compared to those in high-income settings (27%). TBI occurrence is high in Cameroon, and RTIs are the main causes. Disparities in care provision were identified as attributable to financial constraints regarding CT scanning and continuation of care. The data presented can inform preventive interventions to improve care provision and transport policies. Implementation of a universal health insurance may be expected to improve hospital care and reduce the adverse effects of TBI among Cameroonians.

摘要

创伤性脑损伤(TBI)是全球范围内一项巨大的公共卫生挑战。流行病学监测对于制定医疗保健政策至关重要。我们旨在通过在三个转诊创伤中心进行为期5年的回顾性研究,确定喀麦隆TBI的患病率、转归及病因。记录了人口统计学、病因、损伤机制、临床情况及出院状态等数据。两个分类变量之间的比较采用Pearson卡方检验或Fisher精确检验。在18151例创伤病例中,共识别出6248例TBI病例,患病率为34%。TBI病例数逐年增加(2016年为915例,2020年为1406例)。6248名受试者有TBI的人口统计学数据和病因,2178名受试者有详细的临床特征数据。中位年龄为30.0(24.0,41.0)岁。男性受影响更多(80%)。道路交通事件(RTIs;75%)是TBI的主要病因,职业自行车骑手受影响更大(17%)。67.7%的病例进行了计算机断层扫描(CT)成像。在未进行神经影像学检查的597例(27.4%)病例中,311例(52.1%)因经济限制未进行神经影像学检查,其中7%为重度TBI病例。共有341例(19.6%)患者不听从医嘱出院,其中83%存在经济限制。总体人群死亡率为10.3%(2178例中有225例),但与高收入地区患者(27%)相比,重度TBI患者死亡率极高(55%)。喀麦隆TBI发生率很高,RTIs是主要病因。已确定护理提供方面的差异可归因于CT扫描和持续护理方面的经济限制。所呈现的数据可为改善护理提供和交通政策的预防性干预措施提供参考。实施全民健康保险有望改善喀麦隆人的医院护理并减少TBI的不良影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38b0/9879018/eed82291de7a/neur.2022.0053_figure1.jpg

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