Layer G T, Scott-Jupp R H, Maitra T K, Darke S G
Department of Surgery, Poole General Hospital, Dorset, UK.
Postgrad Med J. 1987 Mar;63(737):211-2. doi: 10.1136/pgmj.63.737.211.
A case of peritonitis following perforation of gastric-type mucosa in a Meckel's diverticulum is described. At laparotomy a wax core of a combined diuretic-slow-release potassium preparation was found extruding through the perforation and a further pellet was found free in the peritoneal cavity. Intestinal perforation due to potassium-containing drugs is recognized and led to the development of enteric-coated and slow-release delivery systems. The association of perforation of Meckel's diverticulum with a slow-release potassium perforation has not previously been described.
本文描述了一例梅克尔憩室胃型黏膜穿孔后并发腹膜炎的病例。剖腹探查时发现一种复方利尿-缓释钾制剂的蜡芯从穿孔处挤出,另一个药丸游离于腹腔内。含钾药物导致的肠穿孔已得到认识,并促使了肠溶片和缓释给药系统的发展。梅克尔憩室穿孔与缓释钾制剂穿孔相关联的情况此前尚未见报道。