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一例罕见的伴有下腔静脉侵犯的肾细胞癌:一种危及生命的并发症。

A Rare Case of Renal Cell Carcinoma With Inferior Vena Cava Invasion: A Life-Threatening Complication.

作者信息

Nduji Amarachi J, Rentiya Zubir S, Butt Rowaida, Aiyadurai Sanathan, Annan Albert, Khan Tuba, Mahjabeen Syeda Sarah, Dave Vyapti A, Apata Esther O, Khan Aadil

机构信息

Internal Medicine, Abia State University School Uturu, Uturu Okigwe, NGA.

Department of Surgery, MedStar Georgetown University Hospital, Washington, DC., USA.

出版信息

Cureus. 2022 Dec 26;14(12):e32978. doi: 10.7759/cureus.32978. eCollection 2022 Dec.

DOI:10.7759/cureus.32978
PMID:36712759
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9877276/
Abstract

Renal cell carcinoma (RCC) arises from the renal tubular epithelial cells and comprises a group of heterogenous renal tumors. Renal tumors can metastasize to involve almost any body organ, the common sites being the lung, liver, bone, brain, adrenal gland, head, neck, and rarely, inferior vena cava (IVC), leading to lethal outcomes. We present a case of RCC with IVC invasion in a patient who presented with right-sided flank pain and gross hematuria. His routine biochemical and hematological parameters were unremarkable, and an abdominal examination revealed a complex renal mass with mild hydronephrosis. The patient underwent contrast-enhanced magnetic resonance angiography with venography, which showed a right renal upper polar mass lesion extending into the right vein obliterating it up to its junction with the IVC. Integrating examination and imaging findings were suggestive of right renal RCC. Our case highlights the importance of standard preoperative MRI imaging to assess IVC invasion and its morphologic features including vessel breach or complete occlusion of the IVC.

摘要

肾细胞癌(RCC)起源于肾小管上皮细胞,是一组异质性肾脏肿瘤。肾肿瘤可转移至几乎任何身体器官,常见部位为肺、肝、骨、脑、肾上腺、头、颈,很少转移至下腔静脉(IVC),可导致致命后果。我们报告一例肾细胞癌侵犯下腔静脉的病例,该患者表现为右侧胁腹痛和肉眼血尿。其常规生化和血液学参数无异常,腹部检查发现一个复杂的肾脏肿块伴轻度肾积水。患者接受了增强磁共振血管造影及静脉造影,结果显示右肾上部极肿块病变延伸至右静脉,直至其与下腔静脉的连接处将其闭塞。综合检查和影像学结果提示为右肾肾细胞癌。我们的病例强调了术前标准MRI成像对于评估下腔静脉侵犯及其形态学特征(包括血管破裂或下腔静脉完全闭塞)的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f622/9877276/e44ae0aea3a0/cureus-0014-00000032978-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f622/9877276/ca29c6c710ae/cureus-0014-00000032978-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f622/9877276/00a6b6b3a7ce/cureus-0014-00000032978-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f622/9877276/e44ae0aea3a0/cureus-0014-00000032978-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f622/9877276/ca29c6c710ae/cureus-0014-00000032978-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f622/9877276/00a6b6b3a7ce/cureus-0014-00000032978-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f622/9877276/e44ae0aea3a0/cureus-0014-00000032978-i03.jpg

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本文引用的文献

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Clin Case Rep. 2021 Nov 6;9(11):e05033. doi: 10.1002/ccr3.5033. eCollection 2021 Nov.
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Experience with management of renal cell carcinoma with inferior vena cava/right atrial tumor thrombus.肾细胞癌合并下腔静脉/右心房肿瘤血栓的治疗经验。
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基于多模态影像的肾细胞癌合并下腔静脉瘤栓患者下腔静脉壁肿瘤侵犯预测模型。
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Contrast-enhanced ultrasound in detecting wall invasion and differentiating bland from tumor thrombus during robot-assisted inferior vena cava thrombectomy for renal cell carcinoma.机器人辅助下下腔静脉癌栓取栓术中超声造影对肾细胞癌癌栓壁侵犯及良恶性的鉴别诊断价值
Cancer Imaging. 2019 Dec 2;19(1):79. doi: 10.1186/s40644-019-0265-x.
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Diagnostic Accuracy of MRI for Detecting Inferior Vena Cava Wall Invasion in Renal Cell Carcinoma Tumor Thrombus Using Quantitative and Subjective Analysis.MRI 对肾癌合并瘤栓患者下腔静脉壁侵犯的定量及主观分析诊断准确性研究。
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Eur Urol. 2009 Feb;55(2):452-9. doi: 10.1016/j.eururo.2008.07.053. Epub 2008 Aug 5.