Khalil Mujtaba, Abbas Qalab, Azhar Mohammad Kumael, Aamir Faiqa Binte, Hashmi Shiraz, Ali Sadaqat, Faiz Tahira, Malik Mahim Akmal
Dean's Clinical Research Program, Aga Khan University Hospital, Karachi, Pakistan.
Department of Pediatrics, Aga Khan University Hospital, Karachi, Pakistan.
Crit Care Explor. 2023 Jan 23;5(1):e0833. doi: 10.1097/CCE.0000000000000833. eCollection 2023 Jan.
To assess the utility of the Cardiac Children's Hospital Early Warning Score (C-CHEWS) in the early detection of deterioration.
Single-center longitudinal pilot study.
Pediatric cardiac ICU (PCICU), Aga Khan University.
C-CHEWS and Inadequate Oxygen Delivery (IDO) Index calculation every 2 hours.
A total of 60 children (0 d to 18 yr old).
A single-center longitudinal pilot study was conducted at PCICU. All postoperative extubated patients were assessed and scored between 0 and 11, and these scores were then correlated with the IDO index data available from the T3 platform. Adverse events were defined as a need for cardiopulmonary resuscitation, or reintubation, and death. A total of 920 C-CHEWS and IDO scores were analyzed on 60 patients during the study period. There were 36 males and 24 females, and the median age of the study population was 34 months (interquartile range, 9.0-72.0 mo). Fourteen patients (23.3%) developed adverse events; these included 9 reintubations and 5 cardiopulmonary arrests, resulting in 2 deaths. The area under the curve (AUC) for C-CHEWS scores fell in an acceptable range of 0.956 (95% CI, 0.869-0.992), suggesting an optimal accuracy for identifying early warning signs of cardiopulmonary arrest. Whereas, IDO showed no discriminatory power to detect the adverse events with an AUC of 0.522 (95% CI, 0.389-0.652).
The C-CHEWS tool provides a standardized assessment and approach to deteriorating congenital cardiac surgery patients in recognizing early postoperative deterioration.
评估心脏儿童医院早期预警评分(C-CHEWS)在早期发现病情恶化方面的效用。
单中心纵向试点研究。
阿迦汗大学儿科心脏重症监护病房(PCICU)。
每2小时计算一次C-CHEWS和氧输送不足(IDO)指数。
共60名儿童(0天至18岁)。
在PCICU进行了一项单中心纵向试点研究。对所有术后拔管患者进行评估并在0至11分之间评分,然后将这些评分与T3平台上可用的IDO指数数据相关联。不良事件定义为需要心肺复苏、再次插管或死亡。在研究期间,对60名患者共分析了920个C-CHEWS和IDO评分。有36名男性和24名女性,研究人群的中位年龄为34个月(四分位间距,9.0 - 72.0个月)。14名患者(23.3%)发生了不良事件;其中包括9次再次插管和5次心肺骤停,导致2例死亡。C-CHEWS评分的曲线下面积(AUC)落在可接受范围内,为0.956(95%可信区间,0.869 - 0.992),表明在识别心肺骤停早期预警信号方面具有最佳准确性。而IDO在检测不良事件方面没有鉴别能力,AUC为0.522(95%可信区间,0.389 - 0.652)。
C-CHEWS工具为先天性心脏手术病情恶化患者提供了一种标准化评估方法,有助于识别术后早期病情恶化情况。