陷入恶性循环：游离血红蛋白与肺动脉高压的发病机制 - Suppr

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Caught in a vicious cycle: Cell-free hemoglobin and the pathogenesis of pulmonary hypertension.

作者信息

Gonzales Janae, Fraidenburg Dustin R

机构信息

Department of Medicine University of Illinois at Chicago Chicago Illinois USA.

出版信息

Pulm Circ. 2023 Jan 1;13(1):e12194. doi: 10.1002/pul2.12194. eCollection 2023 Jan.

DOI:10.1002/pul2.12194

PMID:36714058

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9872046/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/21a1/9872046/255f5ec71da0/PUL2-13-e12194-g001.jpg

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Int J Mol Sci. 2022 Apr 26;23(9):4763. doi: 10.3390/ijms23094763.

Hemolysis-induced Lung Vascular Leakage Contributes to the Development of Pulmonary Hypertension.溶血诱导的肺血管渗漏导致肺动脉高压的发生。

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Hemin Causes Lung Microvascular Endothelial Barrier Dysfunction by Necroptotic Cell Death.血红素通过坏死性凋亡导致肺微血管内皮屏障功能障碍。

Am J Respir Cell Mol Biol. 2017 Sep;57(3):307-314. doi: 10.1165/rcmb.2016-0287OC.

Elevation of plasma cell-free hemoglobin in pulmonary arterial hypertension.肺动脉高压中血浆游离血红蛋白水平升高。

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