Ankara Dr. Zekai Tahir Burak Women's Health Training Research Hospital, Ankara, Turkey.
Fetal Pediatr Pathol. 2023 Jun;42(3):367-375. doi: 10.1080/15513815.2023.2166798. Epub 2023 Jan 30.
Placental abruption (PA) is an obstetric emergency. This study investigated the use of platelet indices in PA in its early stages to determine if it could aid in diagnosis. Sixty-two pregnant women with PA and 130 pregnant women who delivered due to idiopathic preterm delivery were included in this case-control study. Blood samples including platelet indices, biochemical, and coagulation parameters were obtained before cesarean section. Maternal and neonatal outcomes were recorded. There was no significant difference between the groups as to hemoglobin, hematocrit, and white blood count. Platelet, mean platelet volume (MPV), and platelet to lymphocyte ratio (PLR) were significantly lower, platelet distribution width (PDW) was significantly higher in the PA patients. In the current study, MPV and PLR were lower and PDW was higher in PA patients. These parameters may be useful in assessment of PA.
胎盘早剥（PA）是一种产科急症。本研究探讨了血小板指数在 PA 早期的应用，以确定其是否有助于诊断。本病例对照研究纳入了 62 例胎盘早剥孕妇和 130 例因特发性早产而分娩的孕妇。在剖宫产前采集包括血小板指数、生化和凝血参数在内的血样。记录母婴结局。两组间血红蛋白、红细胞压积和白细胞计数无显著差异。PA 患者血小板、平均血小板体积（MPV）和血小板与淋巴细胞比值（PLR）显著降低，血小板分布宽度（PDW）显著升高。在本研究中，PA 患者的 MPV 和 PLR 较低，PDW 较高。这些参数可能有助于评估 PA。
