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新生儿感染伊丽莎白菌败血症的临床特征和转归。

Clinical Profile and Outcome of Neonates with Elizabethkingia Sepsis.

机构信息

Undergraduate Student, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India.

Department of Neonatology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, 605006, India.

出版信息

Indian J Pediatr. 2023 Jun;90(6):612-614. doi: 10.1007/s12098-022-04467-8. Epub 2023 Jan 30.

Abstract

Elizabethkingia, an emerging nosocomial pathogen is a gram-negative bacillus causing NICU outbreaks. This case series from a tertiary care hospital, South India describes the clinical profile and outcome of 92 neonates with culture-positive elizabethkingia sepsis over a period of 2 y. Elizabethkingia sepsis predominantly affected preterm neonates and the common clinical features were respiratory distress, apnea, and poor feeding. Meningitis was noted in 68% and mortality was 12%. Antimicrobial susceptibility testing showed that elizabethkingia was susceptible to minocycline and levofloxacin.

摘要

伊丽莎白菌是一种新兴的医院内病原体,属于革兰氏阴性杆菌,可引起 NICU 感染爆发。本病例系列研究来自印度南部一家三级护理医院,共纳入 92 例培养阳性的伊丽莎白菌败血症新生儿,对其临床特征和结局进行了为期 2 年的描述。伊丽莎白菌败血症主要影响早产儿,常见的临床特征是呼吸窘迫、呼吸暂停和喂养不良。68%的患儿并发脑膜炎,死亡率为 12%。药敏试验显示,伊丽莎白菌对米诺环素和左氧氟沙星敏感。

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