Horie Hideyuki, Isoyama Takashi, Ishiyama Kazushi
From the Graduate School of Biomedical Engineering, Tohoku University, Sendai, Miyagi, Japan.
Research Institute of Electrical Communication, Tohoku University, Sendai, Miyagi, Japan.
ASAIO J. 2023 Feb 1;69(2):e73-e79. doi: 10.1097/MAT.0000000000001874. Epub 2022 Dec 19.
This study aimed to design a new wireless left ventricular assist device (LVAD) that solved the driveline problem of current LVADs and the heat problem of the transcutaneous energy transfer system (TETS). Our new wireless LVAD consisted of two blood pumps capable of driving using extracorporeal magnets and an intracorporeal battery pack. When one pump was driven, the other pump was stopped. The battery pack was wirelessly and slowly charged using TETS with low-power transmission, whereas the magnetic pump was driven wirelessly by extracorporeal magnets. We demonstrated the feasibility of our system in a bench-top durability test for 7 days. The distance between the extracorporeal magnets and the magnetic pump was 27.5 mm. Our LVAD system had steadily provided sufficient pressure and flow volume (approximately 108 mmHg and 5.0 L/min, respectively) to the test loop for 7 days. Although loss of synchronism occurred once during the test, it recovered within a few minutes. The results demonstrate the feasibility of the proposed wireless LVAD system. Further technical improvements are required in our system, such as downsizing the electric devices inside the body, to conduct an in vivo test for the next step.
本研究旨在设计一种新型无线左心室辅助装置（LVAD），以解决当前LVAD的驱动线问题和经皮能量传输系统（TETS）的发热问题。我们的新型无线LVAD由两个能够使用体外磁体驱动的血泵和一个体内电池组组成。当一个泵驱动时，另一个泵停止。电池组通过低功率传输的TETS进行无线缓慢充电，而磁泵则由体外磁体无线驱动。我们在台式耐久性测试中进行了7天，证明了我们系统的可行性。体外磁体与磁泵之间的距离为27.5毫米。我们的LVAD系统在7天内持续为测试回路提供了足够的压力和流量（分别约为108 mmHg和5.0 L/min）。尽管测试期间发生了一次同步丢失，但在几分钟内就恢复了。结果证明了所提出的无线LVAD系统的可行性。我们的系统需要进一步的技术改进，例如缩小体内电子设备的尺寸，以便进行下一步的体内测试。
