Cavero-Redondo Iván, Martínez-García Irene, Saz-Lara Alicia, Garcia-Klepzig José Luis, Álvarez-Bueno Celia, Martínez-Vizcaino Vicente
Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Talca, Chile.
Health and Social Research Centre, Universidad de Castilla-La Mancha, Cuenca, Spain.
Eur J Cardiovasc Nurs. 2023 Oct 19;22(7):669-678. doi: 10.1093/eurjcn/zvad018.
This network meta-analysis aimed to compare the effect of different types of physical exercise [endurance training, endurance/resistance training, and high-intensity interval training (HIIT)] on exercise capacity and cardiac function parameters in patients with heart failure with preserved ejection fraction.
A systematic search of the MEDLINE (via PubMed), Scopus, and Web of Science databases was conducted to identify experimental studies addressing the effect of different physical exercise training programmes on exercise capacity and cardiac function in heart failure with preserved ejection fraction. Comparative evaluation of the effect of exercise training type was performed by conducting a standard pairwise meta-analysis and a network meta-analysis for direct and indirect comparisons between exercise training types and controls/non-interventions. Eleven studies were included in the analysis showing that endurance training improves the main exercise capacity parameters (VO2peak, workload, exercise time, peak heart rate, VO2, and 6 min walk distance). Additionally, endurance/resistance training showed a significant effect on VO2peak, workload, early mitral annulus velocity, and early mitral/mitral annulus velocity ratio. Finally, HIIT showed a significant effect on VO2peak, VO2, and the early mitral/mitral annulus velocity ratio.
Our findings support the effect of three different types of physical exercise on exercise capacity, mainly VO2peak. Additionally, endurance/resistance training and HIIT could reverse left ventricular remodelling in patients with heart failure with preserved ejection fraction.
PROSPERO: CRD42021276111.
本网络荟萃分析旨在比较不同类型体育锻炼[耐力训练、耐力/阻力训练和高强度间歇训练（HIIT）]对射血分数保留的心力衰竭患者运动能力和心功能参数的影响。
对MEDLINE（通过PubMed）、Scopus和Web of Science数据库进行系统检索，以识别关于不同体育锻炼训练方案对射血分数保留的心力衰竭患者运动能力和心功能影响的实验研究。通过进行标准的成对荟萃分析以及网络荟萃分析，对运动训练类型的效果进行比较评估以便在运动训练类型与对照/非干预之间进行直接和间接比较。分析纳入了11项研究，结果显示耐力训练可改善主要运动能力参数（最大摄氧量峰值、工作量、运动时间、心率峰值、摄氧量和6分钟步行距离）。此外，耐力/阻力训练对最大摄氧量峰值、工作量、二尖瓣环早期速度以及二尖瓣/二尖瓣环早期速度比值有显著影响。最后，高强度间歇训练对最大摄氧量峰值、摄氧量以及二尖瓣/二尖瓣环早期速度比值有显著影响。
我们的研究结果支持三种不同类型体育锻炼对运动能力的影响，主要是对最大摄氧量峰值的影响。此外，耐力/阻力训练和高强度间歇训练可逆转射血分数保留的心力衰竭患者的左心室重构。
PROSPERO：CRD42021276111。
