Li Binbin, Zhu Wanqing, Shi Di, Che Huilin, Lyu Qinglan, Jiang Bimei
Xiangya School of Medicine, Central South University, Changsha, Hunan, China.
Department of Pathophysiology, Sepsis Translational Medicine Key Laboratory of Hunan Province, Changsha, Hunan, China.
Expert Rev Gastroenterol Hepatol. 2023 Mar;17(3):263-272. doi: 10.1080/17474124.2023.2174968. Epub 2023 Feb 6.
This review summarizes and analyzes the abnormal expression and mechanism of S100A16 in digestive system diseases, which is expected to provide new ideas and methods for adjuvant treatment and prognosis evaluation of digestive system diseases.
Based on original publications found in database systems (PubMed, Cochrane), we introduce the mechanism and research progress of S100A16 in digestive system tumors, inflammatory bowel disease and fatty liver.
S100A16 is closely related to the proliferation, migration, and invasion of digestive system tumor cells. Further, it plays an important role in inflammatory bowel disease and fatty liver.
本综述总结并分析了S100A16在消化系统疾病中的异常表达及其机制，有望为消化系统疾病的辅助治疗和预后评估提供新思路和方法。
基于数据库系统（PubMed、Cochrane）中找到的原始出版物，我们介绍了S100A16在消化系统肿瘤、炎症性肠病和脂肪肝中的机制及研究进展。
S100A16与消化系统肿瘤细胞的增殖、迁移和侵袭密切相关。此外，它在炎症性肠病和脂肪肝中也发挥着重要作用。
