Yong W, Qian K, Zhu W H, Zhao X Y, Liu C, Pan J
Department of General Dentistry, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & NHC Research Center of Engineering and Technology for Computerized Dentistry & NMPA Key Laboratory for Dental Materials, Beijing 100081, China.
Beijing Da Xue Xue Bao Yi Xue Ban. 2023 Feb 18;55(1):88-93. doi: 10.19723/j.issn.1671-167X.2023.01.013.
To compare the clinical effects of pulpotomy with two kinds of calcium silicate materials, and to evaluate the formation of dentin bridge and pulp calcification after pulpotomy of adult permanent teeth.
Patients who visited the General Department of Peking University School and Hospital of Stomatology from November 2017 to September 2019 and planned for pulpotomy on permanent premolars and molars with carious exposed pulp were selected. They were randomly divided into two groups. Bioceramic putty material iRoot BP (iRoot group, =22) and mineral trioxide aggregate MTA (MTA group, =21) were used as pulp capping agents, respectively. The patients were recalled after one year and two years. The clinical efficacy, dentin bridge index (DBI) and pulp calcification index (PCI) were recorded. Blinding method was used for the patients and evaluators.
There was no significant difference in gender, mean age, dentition and tooth position between the two groups (>0.05). Seven cases were lost during the first year (4 cases in iRoot group and 3 cases in MTA group). In the iRoot group, 1 case had transient sensitivity at the time of 1-year follow-up. The cure rate of the two groups was 100% at the time of 2-year follow-up. The proportion of dentin bridge formation was 38.9% one year after operation, 55.6% two years after operation. The proportion of partial or even complete disappearance of root canal image was 5.6% before operation, 38.9% and 55.6% one and two years after operation, respectively. The difference was statistically significant by rank sum test ( < 0.05). There was no significant difference in dentin bridge formation and pulp calcification between the two groups ( < 0.05). DBI and PCI after operation was as the same as those before operation (44.4% cases of DBI and 25% cases of PCI) or gradually increased (55.6% cases of DBI and 75% cases of PCI). Spearman's nonparametric correlation analysis showed that age was positively correlated with preoperative pulp calcification index (PCI0, < 0.05), but not with the dentin bridge index (DBI1, DBI2), pulp calcification index (PCI1, PCI2) and the degree of change (DBI2 . DBI1, PCI1 . PCI0, PCI2 . PCI0) 1-year and 2-year after operation (>0.05).
According to this study, good clinical effects were obtained within 2-year after pulpotomy of adult permanent teeth with MTA and iRoot. In some cases, the root canal system had a tendency of calcification aggravation, and there was no statistical difference in the development of this trend between the two groups.
比较两种硅酸钙材料用于活髓切断术的临床效果,评估成人恒牙活髓切断术后牙本质桥形成及牙髓钙化情况。
选取2017年11月至2019年9月就诊于北京大学口腔医院综合科、计划对龋源性露髓的恒牙前磨牙和磨牙行活髓切断术的患者。将其随机分为两组。分别采用生物陶瓷糊剂材料iRoot BP(iRoot组,n = 22)和三氧化矿物凝聚体MTA(MTA组,n = 21)作为盖髓剂。术后1年和两年对患者进行回访。记录临床疗效、牙本质桥指数(DBI)和牙髓钙化指数(PCI)。对患者和评估者采用盲法。
两组患者在性别、平均年龄、牙列和牙位方面差异无统计学意义(P>0.05)。第一年失访7例(iRoot组4例,MTA组3例)。iRoot组在1年随访时有1例出现短暂敏感症状。两年随访时两组治愈率均为100%。术后1年牙本质桥形成比例为38.9%,术后两年为55.6%。术前根管影像部分或甚至完全消失的比例为5.6%,术后1年和两年分别为38.9%和55.6%。经秩和检验差异有统计学意义(P<0.05)。两组间牙本质桥形成和牙髓钙化情况差异无统计学意义(P<0.05)。术后DBI和PCI与术前相同(DBI为44.4%的病例,PCI为25%的病例)或逐渐升高(DBI为55.6%的病例,PCI为75%的病例)。Spearman非参数相关性分析显示,年龄与术前牙髓钙化指数(PCI0)呈正相关(P<0.05),但与术后1年和2年的牙本质桥指数(DBI1、DBI2)、牙髓钙化指数(PCI1、PCI2)及变化程度(DBI2 - DBI1、PCI1 - PCI0、PCI2 - PCI0)无相关性(P>0.05)。
根据本研究,MTA和iRoot用于成人恒牙活髓切断术后2年内临床效果良好。在某些情况下,根管系统有钙化加重的趋势,两组间这种趋势的发展无统计学差异。