Qian K, Pan J, Zhu W H, Zhao X Y, Liu C, Yong W
Department of General Dentistry, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology & NHC Research Center of Engineering and Technology for Computerized Dentistry & NMPA Key Laboratory for Dental Materials, Beijing 100081, China.
Beijing Da Xue Xue Bao Yi Xue Ban. 2022 Feb 18;54(1):113-118. doi: 10.19723/j.issn.1671-167X.2022.01.018.
To evaluate the clinical characteristics and effectiveness of pulpotomy in mature permanent teeth with bioceramic putty repairmen iRoot and mineral trioxide aggregate (MTA).
Pulpotomy was performed on mature permanent premolars and molars with carious exposures at the Department of General Dentistry of Peking University School and Hospital of Stomatology, from November 2017 to September 2019. The patients were randomly divided into 2 groups, Group iRoot (=22) and Group MTA (=21). In Group iRoot, bioceramic putty repairmen iRoot was used as pulp capping agent, while in Group MTA, mineral trioxide aggregate was used as pulp capping agent. All the patients had signed informed consent forms. The clinical efficacy was evaluated by clinical examinations (temperature and electrical activity test) and imaging examinations 3, 6, and 12 months after surgery. Blinding was used for the patients and evaluators, but due to the obvious differences in the properties of the two pulp capping agents, the blinding method was not used for the treatment provider (the attending physician).
There was no significant difference in gender, average age, dentition and tooth position distribution between the two groups (>0.05). In the study, 7 cases were lost to follow-up 12 months after operation (4 cases in Group iRoot, and 3 cases in Group MTA). One case in each of the two groups had transient sensitivity at the end of the 3-month follow-up, and the pulp vitality was normal at the end of the 6-month follow-up. One case in Group iRoot showed sensitivity at the end of the 12-month follow-up. The success rates of the two groups at the end of 12-month follow-up were 100%, and the cure rates were 94.4% (Group iRoot) and 100% (Group MTA), respectively, and the difference was not statistically significant (>0.05). No cases in Group iRoot had obvious crown discoloration, while 3 cases in Group MTA had.
The clinical characteristics and effectiveness of pulpotomy in mature permanent teeth with bioceramic putty repairmen iRoot were similar with MTA. Bioceramic putty repairmen iRoot is an acceptable material when used in pulpotomy of mature permanent teeth. Because it is not easy to cause tooth discoloration after treatment and is convenient to operate, bioceramic putty repairmen iRoot has a better clinical application prospect.
评估使用生物陶瓷糊剂iRoot和三氧化矿物凝聚体（MTA）进行成熟恒牙牙髓切断术的临床特征和效果。
2017年11月至2019年9月，在北京大学口腔医学院口腔综合科，对患有龋露髓的成熟恒前磨牙和磨牙进行牙髓切断术。将患者随机分为2组，iRoot组（n = 22）和MTA组（n = 21）。iRoot组使用生物陶瓷糊剂iRoot作为盖髓剂，而MTA组使用三氧化矿物凝聚体作为盖髓剂。所有患者均签署了知情同意书。术后3、6和12个月通过临床检查（温度和电活力测试）和影像学检查评估临床疗效。对患者和评估者采用了盲法，但由于两种盖髓剂的性质差异明显，对治疗提供者（主治医师）未采用盲法。
两组在性别、平均年龄、牙列和牙位分布方面无显著差异（P>0.05）。研究中，术后12个月有7例失访（iRoot组4例，MTA组3例）。两组各有1例在3个月随访结束时出现短暂敏感，6个月随访结束时牙髓活力正常。iRoot组有1例在12个月随访结束时出现敏感。两组12个月随访结束时的成功率均为100%，治愈率分别为94.4%（iRoot组）和100%（MTA组），差异无统计学意义（P>0.05）。iRoot组无病例出现明显的冠部变色，而MTA组有3例出现。
使用生物陶瓷糊剂iRoot进行成熟恒牙牙髓切断术的临床特征和效果与MTA相似。生物陶瓷糊剂iRoot用于成熟恒牙牙髓切断术时是一种可接受的材料。由于其治疗后不易导致牙齿变色且操作方便，生物陶瓷糊剂iRoot具有较好的临床应用前景。
