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妊娠性黑素瘤。

Melanoma in pregnancy.

机构信息

Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.

Department of Medical Oncology, Yale School of Medicine, New Haven, CT, USA.

出版信息

Abdom Radiol (NY). 2023 May;48(5):1740-1751. doi: 10.1007/s00261-022-03796-8. Epub 2023 Jan 31.

DOI:10.1007/s00261-022-03796-8
PMID:36719425
Abstract

Melanoma is one of the most common types of cancer diagnosed during pregnancy. Patients with advanced disease require frequent staging examinations (e.g., CT, PET, MRI, ultrasound), which, during pregnancy must be modified from routine protocol to minimize risk to the fetus. We will review the diagnostic and treatment approach to pregnant patients with melanoma, with a discussion and pictorial examples of imaging protocol modifications, and the appearance of metastatic melanoma on radiology exams using modified protocols due to pregnancy.

摘要

黑色素瘤是怀孕期间最常见的癌症类型之一。患有晚期疾病的患者需要频繁进行分期检查(例如 CT、PET、MRI、超声),但在怀孕期间,这些检查必须根据常规方案进行修改,以将对胎儿的风险降至最低。我们将回顾孕妇黑色素瘤的诊断和治疗方法,讨论和举例说明影像学方案修改,并讨论由于怀孕而使用修改后的方案在影像学检查中出现转移性黑色素瘤的情况。

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引用本文的文献

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Melanoma in Pregnancy-Diagnosis, Treatment, and Consequences for Fetal Development and the Maintenance of Pregnancy.妊娠期黑色素瘤——诊断、治疗及对胎儿发育和维持妊娠的影响
Cancers (Basel). 2024 Jun 7;16(12):2173. doi: 10.3390/cancers16122173.

本文引用的文献

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Adjuvant checkpoint blockade following complete local therapy for melanoma metastases.黑色素瘤转移灶完全局部治疗后的辅助性检查点阻断治疗。
Lancet. 2022 Oct 1;400(10358):1082-1083. doi: 10.1016/S0140-6736(22)01748-2. Epub 2022 Sep 10.
2
Melanoma in women of childbearing age and in pregnancy in California, 1994-2015: a population-based cohort study.加利福尼亚州育龄期和妊娠女性的黑色素瘤:1994-2015 年的一项基于人群的队列研究。
J Eur Acad Dermatol Venereol. 2022 Nov;36(11):2025-2035. doi: 10.1111/jdv.18458. Epub 2022 Aug 23.
3
Imaging Cancer in Pregnancy.
妊娠期癌症影像学检查
Radiographics. 2022 Sep-Oct;42(5):1494-1513. doi: 10.1148/rg.220005. Epub 2022 Jul 15.
4
Melanoma in pregnancy: Diagnosis and management in early-stage and advanced disease.妊娠期黑色素瘤:早期和晚期疾病的诊断与管理
Eur J Cancer. 2022 May;166:240-253. doi: 10.1016/j.ejca.2022.02.016. Epub 2022 Mar 21.
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Treat Now or Treat Later: Comparative Effectiveness of Adjuvant Therapy in Resected Stage IIIA Melanoma.现在治疗还是稍后治疗:ⅢA期黑色素瘤切除术后辅助治疗的比较效果
J Am Coll Surg. 2022 Apr 1;234(4):521-528. doi: 10.1097/XCS.0000000000000088.
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25 Years of Adjuvant Therapy in Melanoma: A Perspective on Current Approvals and Insights into Future Directions.黑色素瘤辅助治疗25年:当前获批情况的视角及对未来方向的见解
Curr Oncol Rep. 2022 Apr;24(4):533-542. doi: 10.1007/s11912-022-01232-0. Epub 2022 Feb 22.
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Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone Versus Ipilimumab in Patients With Advanced Melanoma.纳武利尤单抗联合伊匹单抗或纳武利尤单抗对比伊匹单抗治疗晚期黑色素瘤患者的长期结局。
J Clin Oncol. 2022 Jan 10;40(2):127-137. doi: 10.1200/JCO.21.02229. Epub 2021 Nov 24.
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Multimodality Imaging and Genetics of Primary Mucosal Melanomas and Response to Treatment.原发性黏膜黑色素瘤的多模态影像学与遗传学及治疗反应。
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