Pruette Megan E, Zarzar Theodore R, Sheitman Brian B
Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
North Carolina Department of Public Safety-Prisons, Raleigh, North Carolina, USA.
J Correct Health Care. 2023 Apr;29(2):109-114. doi: 10.1089/jchc.21.06.0059. Epub 2023 Jan 31.
The prevalence of serious mental illnesses in prisons is estimated to be significantly higher than in the community. The antipsychotic medication clozapine is very effective in managing treatment-resistant psychosis and may also reduce suicidal and self-injurious behaviors but is underused due to several logistic challenges. A partnership between the North Carolina prison system and University of North Carolina School of Medicine established a consultative system for clozapine initiations that has led to a 390% increase in the number of incarcerated people using clozapine over a 5-year period. This article reviews the benefits and challenges of clozapine use in corrections based on the North Carolina experience and practical strategies on how to expand use in a prison system.
据估计，监狱中严重精神疾病的患病率远高于社区。抗精神病药物氯氮平在治疗难治性精神病方面非常有效，还可能减少自杀和自伤行为，但由于一些后勤方面的挑战，其使用不足。北卡罗来纳州监狱系统与北卡罗来纳大学医学院建立了一个氯氮平启动咨询系统，该系统使得在五年时间里，使用氯氮平的被监禁人员数量增加了390%。本文基于北卡罗来纳州的经验，回顾了在惩教机构使用氯氮平的益处和挑战，以及如何在监狱系统中扩大其使用的实用策略。
