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生长激素型垂体腺瘤继发糖尿病。

Diabetes mellitus secondary to growth hormone-secreting pituitary adenoma.

机构信息

Department of Endocrinology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230032, China.

出版信息

Neuro Endocrinol Lett. 2022 Dec 31;43(7-8):366-371.

Abstract

Growth hormone-secreting pituitary adenoma is a common intracranial benign tumor, characterized by excessive production of growth hormone, which leads to acromegaly or giant disease. An abnormal increase in growth hormone can induce glucose metabolism disorder, which is often diagnosed and treated as type 2 diabetes, because of uncontrollable hyperglycemia, delaying the treatment of the primary disease. This paper reports the diagnosis and treatment data of a patient with growth hormone-secreting pituitary adenoma who was first diagnosed as having diabetes, and reviews the related literature to facilitate a better understanding of the disease.

摘要

生长激素型垂体腺瘤是一种常见的颅内良性肿瘤,其特征是生长激素过度分泌,导致肢端肥大症或巨人症。生长激素的异常增加会引起葡萄糖代谢紊乱,常被误诊为 2 型糖尿病,由于高血糖难以控制,从而延误了对原发病的治疗。本文报告了 1 例以糖尿病首诊的生长激素型垂体腺瘤患者的诊治资料,并复习相关文献,旨在提高对该病的认识。

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